S.cerevisiae - Yeastract

Locus Information

Standard Name	BRE1
Systematic Name	YDL074C
Strain	S288c
Description	E3 ubiquitin ligase; forms heterodimer with Rad6p to regulate K63 polyubiquitination in response to oxidative stress and to monoubiquinate histone H2B-K123, which is required for the subsequent methylation of histone H3-K4 and H3-K79; required for DSBR, transcription, silencing, and checkpoint control; interacts with RNA-binding protein Npl3p, linking histone ubiquitination to mRNA processing; Bre1p-dependent histone ubiquitination promotes pre-mRNA splicing
External sources	Open in SGD Open in KEGG

Gene Sequence Download FASTA View Seq	Sequence hidden
Promoter Sequence Download FASTA	>BRE1 YDL074C TTTAAGTTTTTTGGAGTTTTTAGAAATCAAAATCAACTTGTTTGTTATGCAATGAATGGT CAGCAAAAGATGATGTGAGTATATTTCCATGTCTCTGGATGAATGGAAAGGCAATATTAT TAGTATGGTCATAATTTTGCTGAGGCACTCGAGACACACGGAAGTTAGTTCTATGCTCAA GCTCAATTCAAGGGCAGTATCTATTTGAAGCGAGGTGTCAGAATTTAGAAAGTTTAAAAG TGTGACCCACCATTGGGTCAAAACATCTCTAACCTCCAGTGTACAGTTGCTTCGTGAAGA ATCACACCATTGTCTTAGAACCGTTAGTAGTTTCAAGCGTAAAAAATTTGAGGAGGATTT GCAAAATTTTGTATTTTGTTCTTTATTACTAGCTGACTGATTAGCATTGTTTATGAAATT GATAAACCTGTTCAACGATTGAAATAATTGAGTTTCATAATTGTCCATCAAGAAGCCATC TTGAGACGTAGTCTTTAATCCACATTCATATAGTTGATTATGTATGGCAGGACCCATGCT TAATGAGCAATATGATCTTTAGTGCTACAACAATGCGTATATAGCATACGAAGCACAATC GAGTTCAGAATTGTTTCTCTACCCACGAAAGATAATATTGGGAAAATCACTGGTGAAATT CTGAGATCGTTAATTTCAGTGGATTCAAAAAGAAAGAGCAGATCGACAATAGGCACTAAG GATGTCTTCTAACTTTGAAATGAAGCACCAACTGATCGTACTTTGATCAAACCATCGTTA TTATATAAAAGTGACAAAAGCATTTGATCACGTGATTATAATCACATCCAACGAAACTTT CTTAAAGAAGGCGAAAAAACAAAAAAGAAGAAGATTAAAAAAAGTTGGATGGATGTTGTT TGAACGGTAAACTAACAGAGAGCGCCCCAAGGTTTTTAACAGAGATAGAAAGGGCTTTCA CCGTTTTTATGCTAATCGTGCTAGCTGATAATAATCAGAT
Chr coordinates	Chr IV from 326149-324047