Yeastract
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YEASTRACT+ INESC-ID IST IBB
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Locus Information

Standard Name HEM3
Systematic Name YDL205C
Alias OLE2
Strain S288c
Description Porphobilinogen deaminase; catalyzes the conversion of 4-porphobilinogen to hydroxymethylbilane, the third step in heme biosynthesis; localizes to the cytoplasm and nucleus; expression is regulated by Hap2p-Hap3p, but not by levels of heme; human homolog HMBS can complement yeast mutant and allow growth of haploid null after sporulation of a heterozygous diploid
External sources Open in SGD external link
Open in KEGG external link
Gene Sequence
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Promoter Sequence
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>HEM3 YDL205C
AGCAAAGCTCGCACCCGACTTGCTAGGGTTAGTCCAGTATATCAATCCCGTCTTGTTCTG
ATGACCTGCTTCACCGGGAGCGTTAGCATTTCTACTGTTATTCAAATTCGCGTTCTTATT
GGTAGTCGTATTCCTATTCATGTTGATGATAGTTTGTGGCAAGTTGAGACAAGCAATTGA
ACAAGTTATTACTACTATTGCTACATAATTGATCTGCTTTTCAATCCCTTTTATATATTT
TTTTCATCAAAGTAGCAAGCTTTATCGTTTGAGGGTGGAAATAAGGGTGAACAATAAGGG
GAGATTGCCTATGCGCCTAAACGTCACCGTCTAACCTTGTTCTCCTTTCAACAAAAACGC
CTTGCGTTCTTATTGCTAGGCCACAATTACAAGCATCTCAAATGGGGCATTATCACACCG
GTACCACCGACACATTCTGCTGCTACCCTTGTAGTTTAAGTTAACTTTGCGTCCACTTTT
CGTAATTATTTTGCTCCCTGGCAGCACCGGGGGTAAAGATGTCTTTCTGGCTAATGCAGT
CATCCTTACATTGTCGTTCGTACGGCAGTCCAGGATTTTTGACCATCTTTACGCAGCAAT
TCCCATATAACATTCCTTCTCTCCTTGTCAATTGACCCTGGGGAGCGTCTGACCAATAAG
AAACCGATGAGTAAGCAATGAAGGTCTTTTTTTTGGCTACGAAAATTTCAGCAATTTTTT
AAAGTGAAAAAGTAAAAAAATCAAACATAAAAAAAGAAAGAAAATGAAAAAGTAAAGGAA
CGCTTTATATAAACGAGGCTACTAACTATCTGTATTATTGCTACACATAGCCTGAATTCA
AGGTCATTGGCAGATTGACGCTCGTGTTTGCATGGTACAGGGCTGTATTAGATTTTGAAT
ATTCTGTTCTTCTCATCCCGTATTAATATCTAGAACAATAGAAAAAAAGAAAAGCGAAGA
AAATCTAGATAAATTTGTAGTTGGTAAATACACACGTACT
Chr coordinates Chr IV from 93745-92762
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