Locus Information
Locus Info
Protein Info
GO Info
Orthologs
Standard Name
CDC13
Systematic Name
YDL220C
Alias
EST4
Strain
S288c
Description
Single stranded DNA-binding protein found at TG1-3 telomere G-tails; key roles in regulation of telomerase, telomere end protection, conventional telomere replication; regulates telomere replication through recruitment of specific sub-complexes, essential function is telomere capping; forms homodimer via N-terminus; disruption of dimerization leads to short telomeres; autophagy and proteasome are involved in Cdc13p degradation; differentially phosphorylated through cell cycle
External sources
Open in SGD
Open in KEGG
Gene Sequence
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>CDC13 YDL220C
ATGGATACCTTAGAAGAGCCTGAGTGTCCTCCACATAAAAATCGTATTTTTGTGAGCTCG
AGTAAAGATTTTGAAGGCTATCCCAGCAAAGCAATAGTTCCCGTGCAATTCGTGGCGCTT
TTAACCTCAATACACCTGACTGAAACAAAATGTTTGCTAGGCTTTTCTAATTTTGAGAGG
CGAGGAGATCAATCCCAAGAAGATCAATATTTAATCAAACTGAAGTTCAAAGATAGGGGC
TCGGAGAGGTTAGCCCGGATCACTATTTCCTTACTTTGCCAATACTTTGATATTGAACTG
CCAGATTTAGATTCTGACTCAGGCGCATCCCCAACAGTAATACTGAGAGATATTCACCTT
GAAAGGTTATGTTTTTCAAGTTGTAAAGCTTTATATGTATCAAAACACGGGAACTATACT
CTATTCTTAGAGGACATAAAACCGTTGGATTTGGTAAGTGTGATAAGCACCATATCTACA
AAATCGACAAATAGCAGCAAGCATTCGTCATCAGAACTTATTTCAGAATGTGATTTGAAC
AACTCACTTGTGGATATCTTCAACAATTTAATAGAAATGAATAGAGACGAGAAAAACAGG
TTTAAATTTGTAAAGTTGATTCACTACGATATAGAACTAAAAAAGTTCGTTCAAGACCAA
CAAAAGGTATTATCGCAGAAATCAAAAGCCGCAGCAATTAATCCTTTCTTTGTGCCAAAT
AGACTAGGGATACCTTACATTGAATCCCAAAACGAATTCAACTCGCAGCTTATGACGCTT
AATGTAGATGAACCGACCACAGATATAAGCAACATGGGAGAGGAAATGCATGACAGCGCA
GATCCCATTGAGGATTCAGATTCCTCAACTACCTCCTCTACCGGGAAATATTTCAGCTCA
AAATCCTACATCCAGTCACAGACACCTGAAAGGAAAACAAGCGTACCAAATAATTGGCAC
GATGATGATTCCGGAAGCAAGAGGAAGAGAAAGCTTTCTTTCCACAGTCCGAACGCGTCC
TCAATCCGCAAAGCCATCAGTTATGAGCAACTTTCCCTAGCTAGTGTAGGCTCAGTTGAA
AGGTTAGAGGGCAAAATTGTTGGCATGAATCCACCTCAATTCGCCAGTATAAATGAGTTC
AAATATTGCACATTGAAATTATATTTTACGCAGCTCTTACCAAATGTCCCAGACAAGGTC
CTGGTGCCAGGCGTCAATTGCATTGAGATCGTTATCCCGACGAGAGAGCGAATCTGTGAG
CTCTTCGGTGTTTTAAACTGTCAAAGCGACAAGATATCGGATATTTTACTACTGGAAAAG
CCTGATCGAATTTCCGTCGAAGTTGAAAGGATCCTGTGGGACAATGACAAGACCGCCAGC
CCAGGTATGGCAGTATGGAGTTTGAAGAACATTAGCACCGACACGCAGGCGCAGGCGCAG
GTGCAGGTGCCTGCGCAATCGTCGGCGTCAATCGATCCGTCTCGCACAAGGATGAGCAAA
ATGGCAAGGAAAGACCCCACCATCGAATTCTGTCAGTTGGGACTCGACACTTTTGAGACC
AAATACATAACAATGTTTGGCATGCTAGTCTCCTGCTCGTTTGATAAACCTGCCTTTATA
TCTTTTGTCTTTAGCGATTTTACCAAGAACGATATCGTCCAAAACTATCTTTACGACAGA
TATCTAATAGATTACGAGAACAAGTTAGAGCTGAACGAGGGCTTCAAAGCCATCATGTAC
AAAAACCAATTCGAAACGTTTGACTCTAAGCTCAGAAAAATATTCAACAACGGGCTAAGA
GATCTACAGAACGGCCGCGATGAAAACCTTTCGCAATACGGCATAGTTTGTAAGATGAAT
ATAAAAGTGAAAATGTACAACGGCAAATTGAATGCCATTGTGCGCGAATGTGAGCCGGTC
CCGCATTCCCAAATAAGCAGCATCGCCTCGCCTTCACAGTGCGAACATTTAAGATTGTTC
TACCAACGAGCGTTCAAGAGAATTGGCGAATCCGCAATTTCACGCTATTTCGAAGAGTAC
CGGAGGTTTTTCCCCATACATAGAAACGGTTCTCATCTCGCGAAACTGAGGTTCGATGAA
GTAAAGCATGAACCAAAAAAATCACCCACTACACCAGCTCTCGCAGAACACATACCCGAC
CTGAATGCAGACGTGTCCTCCTTCGATGTAAAGTTCACAGATATATCTTCTCTCTTGGAC
TCCTCGGCTCGCCTCCCGCGCCCACAGCAAACACACAAGAGCAACACATTATACAGTTGC
GAGGGCCGTATCATCGCCATCGAGTACCACGCATCTGATCTCTGCTTCCATATCACGAAT
GAGCTCCCACTTTTACAAACCCGCGGCTTGGCCCCGGAGCGAGTGTTGCAACTACACATC
ATTACCTCCAAGAACTTTGCTTATTTTTTCAACCGCTCAAGCGCCTACTTACAGCGTCAG
CCTCTTGAGGAAAAATATACGCAATTGGCACAATTTCTCGGCCATTCATTTAAATTCAAT
ATAACCTCCTCGCTCACGCTGTTCCCTGACACTACCGTGGCACTCCAGATCTGGTGCCCA
ATTGAATGCACCTTTCGGGAATTGCAACAACAGCTGGCCCATCCGAAGGTTGCAGCGGCT
CCTGATTCAGGGAGTCTTGATTGCGCAATTAATGCTACCGTCAATCCTCTGCGACTTCTT
GCCGCGCAAAATGGCGTCACCGTGAAAAAGGAGGAGGATAATGACGATGACGCCGGAGCC
GTTCCCACCTCGTAA
Promoter Sequence
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>CDC13 YDL220C
ATTTACTTACTTTTATGTAAAGAATATAAAACAATTCTAGACTTTCTTGGCGAAGGTTAT
TGAAGGAAGCGTGAATTCAAAAATCCATCACAGATATTTTGTATTCATTTTTTTGGGGAG
GGCTCCTCTCCGCTCTACTCAACTTCACTGAGAACATAACATGGAAAGATTTTGGTACTT
TATCTTGCGAAAGAAAGATTGCAAATAATGTTTGCTTTTTATTTTCTTCTCGTATATATC
TATAAGGTCAATCTTATTGGTCACTGTCAAGAATGATTGTAACGGGCCCTTCATTAGTTA
AAGAGCAACTCATCATTGCGCCGAATTCACCATCCTTTACTTTTTCCTCACCCAAATCAC
TTCTTAGTAATTTTAAGAATTCTTCATAAAGTTCTTTAGCTATATGACCCTTTTGGGCCA
AATGGAAATCGGGTTTAGTTCCCTTCTTGGTTTTTGCCATCAAAGTGAATTGAGACACGG
ATAGAATTTCACCATTGGCCTCTTTAATATTCTTCTTCCATAGATTTCTGGATTCATCTT
CGAAGATTCTCAAACTAAGAACCTTTTTCGATAATTTATCTATCTCCGCCATAGAATCAT
CAATGGAAATACCTACTAGGAGCATATAACCATGTTTAATACTGTCACATAGATAGAGGT
GTTAGTAAAAAAAATTGGTGCACTAACGAAGCTGAAAAAACCGGTAACATACCTTGAAAT
AACTTTTGAATCGACGACTACAGATGCTTGGCTGACTTTTTGTAAGACAATCTTCATTGT
AAATCCGCTGCTGAATAATATGTGGATTATTTAATATGTACATGCAGCCTTGATTAACGT
GATTATACTTTTTAAACCTTTGATATCCAAATTTTTCAACGTCATAAGAGACGCGAAGGC
CTAGTGAGATGCGAAATGCTAATTCAAAATGGAAATTTAAGAATATATTCATATATGTTT
CTCTTTGGATACGAATGACCGTGGAAACTATCGCCTAAAA
Chr coordinates
Chr IV from 65018-62244