Yeastract
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YEASTRACT+ INESC-ID IST IBB
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Locus Information

Standard Name TPI1
Systematic Name YDR050C
Strain S288c
Description Triose phosphate isomerase, abundant glycolytic enzyme; mRNA half-life is regulated by iron availability; transcription is controlled by activators Reb1p, Gcr1p, and Rap1p through binding sites in the 5' non-coding region; inhibition of Tpi1p activity by PEP (phosphoenolpyruvate) stimulates redox metabolism in respiring cells; E104D mutation in human homolog TPI1 causes a rare autosomal disease; human TPI1 can complement yeast null mutant
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Gene Sequence
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Promoter Sequence
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>TPI1 YDR050C
AAGGATGAGCCAAGAATAAGGGAACAAGATTTTGGTAATTTCCAAAAAATCAATAGCATG
CAGGACGTTATGAAGAAGAGATCTACGTATGGTCATTTCTTCTTCAGATTCCCTCATGGA
GAAAGTGCGGCAGATGTATATGACAGAGTCGCCAGTTTCCAAGAGACTTTATTCAGGCAC
TTCCATGATAGGCAAGAGAGAAGACCCAGAGATGTTGTTGTCCTAGTTACACATGGTATT
TATTCCAGAGTATTCCTGATGAAATGGTTTAGATGGACATACGAAGAGTTTGAATCGTTT
ACCAATGTTCCTAACGGGAGCGTAATGGTGATGGAACTGGACGAATCCATCAATAGATAC
GTCCTGAGGACCGTGCTACCCAAATGGACTGATTGTGAGGGAGACCTAACTACATAGTGT
TTAAAGATTACGGATATTTAACTTACTTAGAATAATGCCATTTTTTTGAGTTATAATAAT
CCTACGTTAGTGTGAGCGGGATTTAAACTGTGAGGACCTTAATACATTCAGACACTTCTG
CGGTATCACCCTACTTATTCCCTTCGAGATTATATCTAGGAACCCATCAGGTTGGTGGAA
GATTACCCGTTCTAAGACTTTTCAGCTTCCTCTATTGATGTTACACCTGGACACCCCTTT
TCTGGCATCCAGTTTTTAATCTTCAGTGGCATGTGAGATTCTCCGAAATTAATTAAAGCA
ATCACACAATTCTCTCGGATACCACCTCGGTTGAAACTGACAGGTGGTTTGTTACGCATG
CTAATGCAAAGGAGCCTATATACCTTTGGCTCGGCTGCTGTAACAGGGAATATAAAGGGC
AGCATAATTTAGGAGTTTAGTGAACTTGCAACATTTACTATTTTCCCTTCTTACGTAAAT
ATTTTTCTTTTTAATTCTAAATCAATCTTTTTCAATTTTTTGTTTGTATTCTTTTCTTGC
TTAAATCTATAACTACAAAAAACACATACATAAACTAAAA
Chr coordinates Chr IV from 556472-555726
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