Yeastract
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YEASTRACT+ INESC-ID IST IBB
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Locus Information

Standard Name SAN1
Systematic Name YDR143C
Strain S288c
Description Ubiquitin-protein ligase; involved in proteasome-dependent degradation of aberrant nuclear proteins; targets substrates with regions of exposed hydrophobicity containing 5 or more contiguous hydrophobic residues; contains intrinsically disordered regions that contribute to substrate recognition; prefers a window of exposed hydrophobicity that causes a particular level of protein insolubility, suggesting that San1p evolved to target highly aggregation-prone proteins
External sources Open in SGD external link
Open in KEGG external link
Gene Sequence
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Promoter Sequence
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>SAN1 YDR143C
GGTGGATTCTATCTTTCTAATTGGTTAAGCGATTTTCAGCTAGTCACAGATAGTCGTTCA
AACATTTGTATACTAGGTATTGCACCGCAGTCAGATCCGACCATTATTTTGGGTGATAAC
TTCTTAGCTAATACTTACGTGGTATATGATCTGGACAATATGGAGATATCAATGGCTCAG
GCTAACTTCAGCGACGACGGTGAATACATTGAGATTATAGAGAGCGCGGTTCCAAGTGCT
CTTAAAGCACCTGGTTACTCAAGCACTTGGTCTACATATGAAAGTATTGTCTCCGGCGGC
AACATGTTTTCCACGGCAGCTAACTCCAGTATATCGTACTTTGCTTCCACGTCTCATTCG
GCAACAAGTTCTTCCAGCTCCAAAGGCCAAAAAACCCAAACAAGTACGACAGCTCTCTCT
ATTTCAAAATCTACCTCAAGTACTTCCTCAACAGGAATGTTATCTCCCACCTCAAGTTCA
TCTACGAGAAAAGAAAACGGAGGACACAATCTGAATCCTCCATTTTTCGCCAGGTTCATT
ACAGCTATTTTTCATCACATTTGATAAATCCCTCCCTCCATATAAGCATTTACTAGACTT
TAAAAGTTGCAATGTATATCTGGAGGTATAACATTGTACATTACTTGAAAGAAAAGCGTC
TTTTAACGTAAAATAAATAATACTGTTCTTTTTTATTGTTACTGGCTTCTTAATCAACAA
TTATATACTTCGACGCAAAAAGCCGGGTAAAACATTCTATCTGCCATTGTCAAAAAATAT
GAAAGAATTTTTTACATATAACTACATTGCATTAGTATCACCAAATCAATAATGAAATAA
TAGCTAAAAACTATATATTGAAGGAAATATAGTTTATCATATATATCCTCTAGTGAAGCT
ACTATAGATAGAAATTATTTAGCATTTCAGGATAGTTCGTTTCTCCCTTTTTTCCCCTTT
GTTTTCTCTCATAGTCTTGTAACCTCAGCTTTTGTTCATT
Chr coordinates Chr IV from 743874-742042
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