Yeastract
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YEASTRACT+ INESC-ID IST IBB
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Locus Information

Standard Name SIR4
Systematic Name YDR227W
Alias ASD1, STE9, UTH2
Strain S288c
Description SIR protein involved in assembly of silent chromatin domains; silent information regulator (SIR) along with SIR2 and SIR3; involved in assembly of silent chromatin domains at telomeres and the silent mating-type loci; some SIR4 alleles prolong lifespan; required for Ku-mediated telomerase recruitment, telomere lengthening, and telomere hypercluster formation in quiescent yeast cells
External sources Open in SGD external link
Open in KEGG external link
Gene Sequence
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Promoter Sequence
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>SIR4 YDR227W
GTTTCCATGCCGCTCACTTGGCCACTGGTGACATGTTGAGATCTCAAATCGCAAAGGGCA
CTCAATTAGGTTTGGAAGCAAAGAAAATTATGGACCAAGGTGGTTTAGTCTCTGATGACA
TTATGGTTAACATGATCAAGGATGAATTGACCAACAATCCAGCTTGTAAGAATGGGTTCA
TCTTGGACGGTTTCCCAAGAACCATTCCTCAGGCTGAAAAATTGGACCAAATGTTGAAAG
AACAAGGAACTCCTTTGGAAAAAGCCATCGAATTGAAGGTTGATGATGAATTGTTGGTTG
CCAGAATTACCGGTAGATTAATTCACCCAGCCTCTGGCAGATCCTACCACAAGATCTTTA
ACCCACCAAAGGAAGACATGAAGGATGACGTCACCGGTGAAGCTTTAGTTCAAAGATCTG
ATGACAATGCAGACGCCTTGAAGAAGAGATTAGCTGCTTACCATGCTCAAACCGAACCAA
TTGTTGACTTTTACAAAAAGACCGGTATCTGGGCTGGTGTTGATGCTTCCCAACCTCCTG
CTACTGTTTGGGCTGACATCTTGAACAAGCTAGGTAAGGATTAATGACCTTGCGCAATGT
CTTCTAAATATCTTTTCTTTTTTTTAAATTAATGAAAATATAATAAATTTTTGTATGTGA
GTACATATATCCGCAGTATACTATAAATGAAATAATAACATAAGTGTTTGTAACTGGCTA
TAACGTCCTTAAACATGTGCACTGCCATTAAGTACTTAGTCAATATTTTTATCGTTGAGA
ACGAACGCAAATCATATTACTAAATAGATGAACAAAAGCGCATCACATAAACAAAAACGG
TATAACAGTAATAGTGAAGCTTTTTATAAACCTATAACGAAATAAGCGCTTTTCAGGTTT
TATAATTCAGTCAGAGTTCTAACTGGACATCGTTTTGCAGGGGATAAAAAAAAAAAGGAA
GCTTCAACCCACAATACCAAAAAAGCGAAGAAAACAGCCA
Chr coordinates Chr IV from 917571-921647
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