Locus Information
Locus Info
Protein Info
GO Info
Orthologs
Metabolism
Standard Name
YPR1
Systematic Name
YDR368W
Strain
S288c
Description
NADPH-dependent aldo-keto reductase; reduces multiple substrates including 2-methylbutyraldehyde and D,L-glyceraldehyde, expression is induced by osmotic and oxidative stress; functionally redundant with other aldo-keto reductases; protein abundance increases in response to DNA replication stress; YPR1 has a paralog, GCY1, that arose from the whole genome duplication; human homolog AKR1B1 can complement yeast null mutant
External sources
Open in SGD
Open in KEGG
Gene Sequence
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Sequence hidden
Promoter Sequence
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>YPR1 YDR368W
TTTTGTTAACTTGTAAGGATTCGAAGCAAAGCACAATTTTACTAACCTGTTCTCAAACAT
ATTTTTTTTTCATAGTCTTTTTTGGGGTTTATGCCGCTATACCTTGCAGTTGAGATTGTC
TTAGGTATTTCCATTCTAAACAAATGCAGTGGTGCTTATGGTATTTTAGCATTGTTCACG
GGTCATCCGTTGGATTTTATGCAATGGATAGCATATCTTTGGTCGGTATTTACATTAATC
GTATTCTCACAAGGGCTGTATTTGATTCATAAGCCAAACTTGCTGGTATTTTCGCAAATC
TGCGTACTTTATACAATCGATACCATTTCCACTTGTTTTTTTACTCTATGGTTTACCACG
CAATGGTTCACCTTGGAAGACACTGCTAATATTGATGGAAATAATGCACTACAAAGTAAC
CCAATATCGACAGGTAAGCTGACAGAACGTGGTATTGATATAAGTAAACAAAGTGCAACT
GAAAGCTACGAATATACCATGACTATTTTAATTACGTTGGTGTCATTGATATTCAGGTTC
TACTTTAACTTCATTTTGGCATCTTTTGTTCAAGAATTGTTACACCACCCCAAATATTTA
GTTGATAGGGATGACGTAGAACAAAACTTGAAAAACAAGCCTATTTGGAAAAGACTGTGG
GCTAAGAGCCAAAAAGGTTGTTATAAGCTATGTAAGAATTTGTTAGAGTAAATAGTAAAA
TAAAGCCCTAGCGTTATAGCGTTTTACACTGATGAAGAAATGTTTCTATTCTGACATCAT
AAAATCATTCTCACTGATGCTATTGTCACTTTTCATCACGTGTGTATTTAAGTAGCTCTT
ACGTAATTTTGAAAAAAAAGGAAAAAGGAAACTATATAGCACGCAATTCCCTATTTGGTT
GCAATTCAATTCCGTGAAACCCTTTTCTTTTCTAAAGTGATAATAAAGTAACTTTGCAAT
ATAATCAGGTCGCAAATATACCCACAGATAATAATCTACC
Chr coordinates
Chr IV from 1213904-1214842