Yeastract
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YEASTRACT+ INESC-ID IST IBB
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Locus Information

Standard Name UGO1
Systematic Name YDR470C
Strain S288c
Description Outer membrane component of the mitochondrial fusion machinery; binds to Fzo1p and Mgm1p to link these two GTPases during mitochondrial fusion; involved in fusion of both the outer and inner membranes; facilitates dimerization of Fzo1p during fusion; import into the outer membrane is mediated by Tom70p and Mim1p; has similarity to carrier proteins but likely not a transporter; similar to human SLC25A46 implicated in optic atroprophy spectrum disorder and Leigh syndrome
External sources Open in SGD external link
Open in KEGG external link
Gene Sequence
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Promoter Sequence
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>UGO1 YDR470C
TACCAGCGTAACGACCACGAACAACGACAGCTACGATAATACGAAAATTTGTTAGTAAAT
TTTTCTATTTCTAATGATATTTTGAAATAAAAGAGAAGTGGATTTAGCTTTTTGTTCCCT
GGAAAGTTAACATTGATTAGATAGCTATCTGTTCAACTCAGTGTTGAACACTGATAAATT
ACATTTTCCATGTGCCTTTTTTGCAGATCGACACGATTGGTCGTGAATGTGGTGCTCCCC
GGGCCCTCTCTTTTTTACTGGCACAATTGGTACCTCCTACAATGACAATACAATCATGTA
CTGCTTTCCATATTGTTTGTCCCTCAGATTGTACAATTTCCCATCTTATGCACCTGAAAG
TCCCCTTTTATTCGATATCTTAATTAGAGCGTTTGCTCTGTTAAATTTACGTACCAACTT
TACCTGCTTTCAAAAATTTAGCCATGGTTATATTGATTTCTTTGAGCGACTCTTTCTTTT
CACCAAAACGCCCTAATAGTCACTAAGGGCAAACCATTAAATGTGTATATTGCTGCTTTT
GATATTATAAACTGACGTGGAAAGGCAAAAGTTTCAACGTACCCTCCGCGCAATCTAGGC
AGACGCCGGGTTTGACAGGTAGTACCAAAAACAAAACGCTAGCTGCAGCCAATGCCGACT
TTCAATAATCTCCGCCTAGACAGCACTACTGCTCGGATTAGTTTTGAAAGGACTTCCACT
CCCATGAAAAACAAAATACTACTTCTCTTCACCCAAAAAAAGGGTAATATATGTGTGGGT
GGAAAATGATTGGGTGTTTAAAAACATAGTCTTCAAATTGGTAAGAATTGGAAAAAACAA
GGTGAAATAGGAAACTTAACAGGAATATAGCATTAAGTACCCTTTACAACTATGGTTTTT
AATATTAGCAAAGGTAGAGAGAAAAGGAATTTTAATTGATTTGCCTTAATTCTCTGCCGA
TTTTTGGTTTCCAATAGTATAGGTTTAACTCAACCCCCCA
Chr coordinates Chr IV from 1401214-1399706
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