Yeastract
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YEASTRACT+ INESC-ID IST IBB
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Locus Information

Standard Name AFG3
Systematic Name YER017C
Alias YTA10
Strain S288c
Description Mitochondrial inner membrane m-AAA protease component; mediates degradation of misfolded or unassembled proteins; also required for correct assembly of mitochondrial enzyme complexes; involved in cytoplasmic mRNA translation and aging; expression of human homolog AFG3L2 can complement yeast yta12 afg3 double mutant
External sources Open in SGD external link
Open in KEGG external link
Gene Sequence
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Promoter Sequence
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>AFG3 YER017C
TTTTTTTCCCTTTTTACGCGGAAAGCGCAAATTTCCTCGAAGATTTAAGCCAAACCAAAA
TAAATCAAACCAAACCAAAACAAAACAAAAACAAAAACAAAAACAGGCTAAGCCGATTCA
ATTAAAACCGCTCATACGTATACAACACATACACACATACAAGAATGGCCAGCATAGACG
CATTTTCGGACCTTGAGCGCCGGATGGACGGGTTCCAAAAGGACGTGGCCCAGGTACTGG
CACGTCAGCAAAACCACGCGCGCCAACAGCTGCAACAGTTCCAAGCGGAAATGCGTCAAT
TACATAACCAACACCAACATCTCATAGATGAACTGCAACGGCTTGCCACCCAGCGCACCG
CTCTGCAGCAACAAATACATGCGGCCCAACAAGCTACAAATACCACCAGAGAGCAGTGGA
GAAGCTATCACGAGCGTGAATCTGAGTTATCTAGACGGCAGTCGACCTTAGCAGCCCAAT
CGCGCGAGCTGGACTCGCTGCTGCAACAGCGTGGTAAAGAGTGTGTCCAATTACGCGCAC
GTTGGGCTGCGCAGTCGGGTAACGATGCCGCAGAGGTCGCACTGTACGAACGGCTGTTGC
AGCTTCGTGTACTACCCGGAGCCAGCGATGTGCATGACGTACGTTTCGTATTCGGCGATG
ATTCACGCTGCTGGATCGAAGTCGCGATGCACGGAGACCACGTGATCGGAAACTCTCACC
CGGCGCTGGACCCCAAGAGTCGGGCAACACTTGAGCACGTGCTTACCGTCCAGGGCGACC
TCGCGGCATTTTTAGTCGTGGCCCGCGATATGCTTCTGGCATCTTTATAACGCCTTTATA
CGCATCTGTTCAGTTTATTCTGGGCCTATGATTTAGATGAGGAATAAATTGGTTCTTACT
GTCTATACATAACTTTTACAAGGACCCATTCTATATTAAAGGAGATTAACGCAGTCTTCA
AATAAAGGCATCATCCACTTATTTTATAATATACTAAGTG
Chr coordinates Chr V from 191788-189503
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