Locus Information
Locus Info
Protein Info
GO Info
Orthologs
Standard Name
AFG3
Systematic Name
YER017C
Alias
YTA10
Strain
S288c
Description
Mitochondrial inner membrane m-AAA protease component; mediates degradation of misfolded or unassembled proteins; also required for correct assembly of mitochondrial enzyme complexes; involved in cytoplasmic mRNA translation and aging; expression of human homolog AFG3L2 can complement yeast yta12 afg3 double mutant
External sources
Open in SGD
Open in KEGG
Gene Sequence
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Sequence hidden
Promoter Sequence
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>AFG3 YER017C
TTTTTTTCCCTTTTTACGCGGAAAGCGCAAATTTCCTCGAAGATTTAAGCCAAACCAAAA
TAAATCAAACCAAACCAAAACAAAACAAAAACAAAAACAAAAACAGGCTAAGCCGATTCA
ATTAAAACCGCTCATACGTATACAACACATACACACATACAAGAATGGCCAGCATAGACG
CATTTTCGGACCTTGAGCGCCGGATGGACGGGTTCCAAAAGGACGTGGCCCAGGTACTGG
CACGTCAGCAAAACCACGCGCGCCAACAGCTGCAACAGTTCCAAGCGGAAATGCGTCAAT
TACATAACCAACACCAACATCTCATAGATGAACTGCAACGGCTTGCCACCCAGCGCACCG
CTCTGCAGCAACAAATACATGCGGCCCAACAAGCTACAAATACCACCAGAGAGCAGTGGA
GAAGCTATCACGAGCGTGAATCTGAGTTATCTAGACGGCAGTCGACCTTAGCAGCCCAAT
CGCGCGAGCTGGACTCGCTGCTGCAACAGCGTGGTAAAGAGTGTGTCCAATTACGCGCAC
GTTGGGCTGCGCAGTCGGGTAACGATGCCGCAGAGGTCGCACTGTACGAACGGCTGTTGC
AGCTTCGTGTACTACCCGGAGCCAGCGATGTGCATGACGTACGTTTCGTATTCGGCGATG
ATTCACGCTGCTGGATCGAAGTCGCGATGCACGGAGACCACGTGATCGGAAACTCTCACC
CGGCGCTGGACCCCAAGAGTCGGGCAACACTTGAGCACGTGCTTACCGTCCAGGGCGACC
TCGCGGCATTTTTAGTCGTGGCCCGCGATATGCTTCTGGCATCTTTATAACGCCTTTATA
CGCATCTGTTCAGTTTATTCTGGGCCTATGATTTAGATGAGGAATAAATTGGTTCTTACT
GTCTATACATAACTTTTACAAGGACCCATTCTATATTAAAGGAGATTAACGCAGTCTTCA
AATAAAGGCATCATCCACTTATTTTATAATATACTAAGTG
Chr coordinates
Chr V from 191788-189503