Yeastract
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YEASTRACT+ INESC-ID IST IBB
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Locus Information

Standard Name ISC1
Systematic Name YER019W
Strain S288c
Description Inositol phosphosphingolipid phospholipase C; hydrolyzes complex sphingolipids to produce ceramide; regulates the spindle assembly checkpoint upstream of PP2A-Cdc55; activates genes required for non-fermentable carbon source metabolism during the diauxic shift; mediates Na+ and Li+ halotolerance; activated by phosphatidylserine, cardiolipin and phosphatidylglycerol; mitochondrial outer membrane protein; ortholog of mammalian neutral sphingomyelinase type 2
External sources Open in SGD external link
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Gene Sequence
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Promoter Sequence
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>ISC1 YER019W
ATATTATAAAATAAGTGGATGATGCCTTTATTTGAAGACTGCGTTAATCTCCTTTAATAT
AGAATGGGTCCTTGTAAAAGTTATGTATAGACAGTAAGAACCAATTTATTCCTCATCTAA
ATCATAGGCCCAGAATAAACTGAACAGATGCGTATAAAGGCGTTATAAAGATGCCAGAAG
CATATCGCGGGCCACGACTAAAAATGCCGCGAGGTCGCCCTGGACGGTAAGCACGTGCTC
AAGTGTTGCCCGACTCTTGGGGTCCAGCGCCGGGTGAGAGTTTCCGATCACGTGGTCTCC
GTGCATCGCGACTTCGATCCAGCAGCGTGAATCATCGCCGAATACGAAACGTACGTCATG
CACATCGCTGGCTCCGGGTAGTACACGAAGCTGCAACAGCCGTTCGTACAGTGCGACCTC
TGCGGCATCGTTACCCGACTGCGCAGCCCAACGTGCGCGTAATTGGACACACTCTTTACC
ACGCTGTTGCAGCAGCGAGTCCAGCTCGCGCGATTGGGCTGCTAAGGTCGACTGCCGTCT
AGATAACTCAGATTCACGCTCGTGATAGCTTCTCCACTGCTCTCTGGTGGTATTTGTAGC
TTGTTGGGCCGCATGTATTTGTTGCTGCAGAGCGGTGCGCTGGGTGGCAAGCCGTTGCAG
TTCATCTATGAGATGTTGGTGTTGGTTATGTAATTGACGCATTTCCGCTTGGAACTGTTG
CAGCTGTTGGCGCGCGTGGTTTTGCTGACGTGCCAGTACCTGGGCCACGTCCTTTTGGAA
CCCGTCCATCCGGCGCTCAAGGTCCGAAAATGCGTCTATGCTGGCCATTCTTGTATGTGT
GTATGTGTTGTATACGTATGAGCGGTTTTAATTGAATCGGCTTAGCCTGTTTTTGTTTTT
GTTTTTGTTTTGTTTTGGTTTGGTTTGATTTATTTTGGTTTGGCTTAAATCTTCGAGGAA
ATTTGCGCTTTCCGCGTAAAAAGGGAAAAAAAGCAGATAT
Chr coordinates Chr V from 192797-194230
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