Yeastract
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YEASTRACT+ INESC-ID IST IBB
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Locus Information

Standard Name SLX8
Systematic Name YER116C
Strain S288c
Description Subunit of Slx5-Slx8 SUMO-targeted ubiquitin ligase (STUbL) complex; role in proteolysis of spindle positioning protein Kar9, DNA repair proteins Rad52p and Rad57p; stimulated by SUMO-modified substrates; contains a C-terminal RING domain; forms nuclear foci upon DNA replication stress; required for maintenance of genome integrity like human ortholog RNF
External sources Open in SGD external link
Open in KEGG external link
Gene Sequence
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Promoter Sequence
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>SLX8 YER116C
GGACATAAATGATCTTACAACAATTGGACATTTTTGGAGTTTGTATATTCCGCATAGAAC
TTCCAATAGTCTTAACAAAAGTAACCTTCTCAGTAATCAGTTGGAAAGGCATCCATTTAA
CGCTTTAAGGCCCAGAAGTAGATTTCGCTATCTGGATGTAGGCATGGAGAAGCCATTAAG
GATAAATTTGGCATCTTCCATTTTGGCTATCCACTATATTCATTGATAGACTCCCACATT
TCTTGAACATTGCTTGTCTCAATTGTAACATTCAGTCTCGGGAATATACTTTTTTATTTG
TTGATTGACGACATCTTGTGTGATTTAAATGGGTATTTCCACTTGTTTCGGTTTTAACAT
ACAGAAATTCTGAATTTTGTACCTTGAGCACCGTTACCTGACATTTTTGCTGTATTATTA
TCGTGATTTCTCGATTATTTCGAAATAGCAATATTACTCGCTTAATCAATATTCAAAATC
TATATACTTCTTGATTATAACTCTCCATCCAACTGAAAAGAAACCGTGGGCTTCCTTCCA
GTAAGTCTCAGAGGCGCAAGCCGGGACAGCACCGTATTAGTTTCAGTTTCCCGCCCAAGT
GAAAGGTAGTTAGCTACTGTCCCTCCCCCGTGCACAGCATGTTGGAGGGTTCCCAGCAGC
TGCCGGTGGGGAAGAGAACAGTAAGCATGAGAGGAACCCTCGCTTTGCCGAGAATTGAAG
GAGACGGCTCCTAATAGAAAAAAATCTTTCAAATTAAACAAAAAATGTTTGGGTTCACAA
AAGTGTACGGATGTATACAACAGGGAAAGAAAGAACTGTTTTCTACATCTATTTGTATTT
TAGGAAATTACAGAAGAGAAGGGATAATATGTCAGATATTAGAGCATGCGGAAGATTAGT
AGGAACAACTTTCTTTCTTCGATCAACAGTACTTTTTCCCCTACTGAGTCAATATAAAGG
GGCGGCCAAGTAACAAACGAGTAAATTAATTACACCTTGT
Chr coordinates Chr V from 396172-395348
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