Yeastract
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YEASTRACT+ INESC-ID IST IBB
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Locus Information

Standard Name GRX4
Systematic Name YER174C
Strain S288c
Description Glutathione-dependent oxidoreductase and glutathione S-transferase; hydroperoxide/superoxide-radical responsive monothiol glutaredoxin subfamily member with Grx3p and Grx5p; protects cells from oxidative damage with GRX3 and GRX5; with Grx3p, promotes dissociation of Aft1p from iron regulon gene promoters and subsequent nuclear export in iron-replete conditions, regulating iron homeostasis; involved with Grx3p in Sir2p deglutathionylation, restoring deacetylase activity after disulfide stress
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Gene Sequence
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Promoter Sequence
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>GRX4 YER174C
GGAAGCGATCTCTCCGCTACCATGATTAAGACTGCAGAAGTAATAAAGGAAGGAAGTCCT
GATACATACAAAAACGTTTCATTTAAGATTTCTTCAAGTGATGATTTTAAATTCCTAGGC
GCGGATTCAGTAGACAAACAGAAAATTGATATGATTACCGCAGTAGAATGTGCTCATTGG
TTCGATTTCGAAAAATTTCAGCGATCTGCTTATGCCAATTTGAGAAAAGATGGTACTATC
GCTATTTGGGGTTATGCGGACCCAATTTTCCCGGACTACCCTGAATTTGATGATCTGATG
ATTGAAGTTCCTTACGGGAAGCAAGGACTGGGACCCTATTGGGAACAACCGGGGAGATCT
CGCCTTCGTAATATGCTGAAAGACTCTCACTTAGACCCAGAACTTTTCCATGATATACAA
GTTTCATATTTTTGTGCAGAAGATGTGAGAGACAAAGTAAAACTCCACCAGCATACAAAG
AAGCCATTGCTAATCAGAAAGCAGGTCACCCTAGTGGAGTTTGCAGATTATGTCAGAACC
TGGAGCGCTTACCATCAGTGGAAGCAGGATCCAAAGAACAAAGATAAAGAAGATGTAGCA
GATTGGTTTATTAAAGAGTCACTAAGGAGGAGGCCGGAACTTTCCACCAACACCAAAATT
GAAGTTGTTTGGAATACTTTTTACAAACTTGGCAAAAGGGTCTGAAAATTTCAGCCAATA
AGCATTATATTCGTGAAATTTTAGTAAGAGCGCGCGTTTTAATTGGTGAAGCCTCGCGAC
GTATTCACAGATGTCCTAGAAAAAGTTACCATATCTGAAGACTGGTTGATATTTAGCTTA
AATAGCATATTAATACTGTACCAGTTGAACCATTTTTTAATCTGTTACTGCCAGGAACGT
TGATTCGTTTTCCCGGTAACATTGTTGTCTTTGGGTACTGAGCATATTTCATTTTTCCAC
TTACATATAACTAAATTTCTGTGCTCTTCCTCCAATAAAT
Chr coordinates Chr V from 539168-538434
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