Locus Information
Locus Info
Protein Info
GO Info
Orthologs
Standard Name
COS4
Systematic Name
YFL062W
Strain
S288c
Description
Endosomal protein involved in turnover of plasma membrane proteins; member of the DUP380 subfamily of conserved, often subtelomeric COS genes; required for the multivesicular vesicle body sorting pathway that internalizes plasma membrane proteins for degradation; Cos proteins provide ubiquitin in trans for nonubiquitinated cargo proteins
External sources
Open in SGD
Open in KEGG
Gene Sequence
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>COS4 YFL062W
ATGAAAGAAAATGAACTTAAAAATGAGAAAAGTGTAGATGTATTATCTTTCAAACAGCTC
GAATCTCAAAAGATTGTTCTACCTCAAGATCTTTTCAGAAGCAGCTTTACCTGGTTTTGT
TATGAAATTTACAAGTCCTTAGCGTTTCGCATCTGGATGCTATTATGGCTACCACTTAGC
GTCTGGTGGAAGCTTTCCAACAATTGGATTTACCCGCTTATGGTTTCACTTCTTGTCCTG
TTTTGGGGACCAGTATTTGTTCTTGTTATTTTTAGACTTTCTCGTAAACGTTCCTTATCG
AAACAACTCACTCAGTTTTGCAAAGAGATTACTAAAAGCACACCAAGTTCGGATCCTCAT
GATTGGGAAGTTGTTGCAGCAAATCTAAATTCGTACTTATATGAAAATAAGGCTTGGAAT
ATTAGGTACTTTTTCTTCAATGCCATGGGCTGCCAAGAAGCGTTCAGAACAACCCTTCTC
GAACCCTTCTCTTTGAAAAAAGACGAAGCTGCCAAGGTTAAGTCATTTAAGGATTCCGTC
CCTTACATTGAAGAAGCATTGGGAGTTTATTTTAGAGAAGTTGAAAAACAATGGAAGTTG
TTTAATTCTGAGAAATCATGGAGCCCTGTTGGCCTGGAAGATGCTAAACTTCCCAAGGAA
GCTTACCGATTTAAGCTTACTTGGTTTTTAAAGAGGATTTCCAATATTTTTATGTTGATA
CCATTCCTTAATTTTTTGTGCTGCATATATGTGTCACGGGGAATGTGCCTTCTATTACGC
ACCTTGTATCTCGGGTGGATTCTTTTCATGTTGGTACAAGGTTTCCAAAATATAAGGGTT
TTGATTATGAGCATGGAACACAAGATGCAGTTCTTGTCGACTATTATAAATGAGCAAGAA
AGTGGTGCGAATGGATGGGACGAAATTGCAAGGAAAATGAATAGGTACTTGTTTGAGAAA
AAAGTCTGGAAGAATGAAGAGTTTTTCTTTGACGGGATTGACTGTGAATGGTTTTTTAGC
CACTTCTTCTACCGCGTTCTATCTGCGAAGAAATCTATGCGGGCTCTATCATTGAATGTG
GAACTATGGCCATATATTAAAGAAGCGCAATTATCCTGCAGTGAGGAGTCCTTAGCGTAA
Promoter Sequence
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>COS4 YFL062W
ACTCAATTTATATACACTTATGCCAATATTACAAAAAAATCACCACTAAAATCACCTAAA
CATAAAAATATTCTATCCTTCAACAATAATACATAAACACACTCAATTGCGTATCAATAC
CACCATGAGGTCATTAACTTAAATGTTCCTTAATACCGTCATACCACTATGCTCTATTCC
ATATATTGTAATATAACTGTACTCTATAGTCATACAGACGCTTTTACTTCACCCTATCTT
CTCATACTATTGTCATAGAATCGCACACTGACGCATGATTAAAACGAATAATTTTTACTA
TAAGGCCTCCCATCCGTGCTCTATCCTTTTGTTTGAAACATTTATATACAGAATCTCAAA
GCAAGCGGGAGAAGTAGTAATTACCCAGAGGTCATGCATGATCTTAGCACCACCGTACCT
CTAAGTTTTGCTTTGAGCCTTTTTACAGTGACATCAAACATAAGGAGAAAAAATGGTATT
GAAAGGTTATCAATATAGGGAAATAAATTGGTTCTATGAATCTTCATGTAAGATACTCGT
AGGACAGACTCTTTCCTGTGTAAATATTTGTGACAGCTACGTCTATTTTCTATTAGATAT
TTACACATTTTTGTCACAGGCAATCTACGCTTAAAATATACGTTTCATTTTGGGTAACAA
CTGCTGTGCGAACAGTGACATTGCTGGTCGCACCTTAAATGTAAACCAAAGTTACGGCAC
ACCGTGATGTACCCTCATACAAAGCTTTGTAAAAGTATTATTACGATTATCGAGTAACTT
AGATAGAAAACCGGAAATGAAATGGACTCCCTTTTCGAATAGTAGAGTTTCTGTGCCTAA
AATAGCCCAACATTGTTGCCCTTTTTCTATCACGAGGTTACTGAGCCATTGCATGAACGC
GCGCGCCTCGGCGGCTTTTTTTTCTACTCTATAAAAGCGAAAAGCCAGAAGTTACTATCT
CGAATAAAAAACCCCTCGAACTGCCATCTCATTACCGAAA
Chr coordinates
Chr VI from 6426-7565