Yeastract
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YEASTRACT+ INESC-ID IST IBB
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Locus Information

Standard Name ATG18
Systematic Name YFR021W
Alias AUT10, CVT18, NMR1, SVP1
Strain S288c
Description Phosphoinositide binding protein; required for vesicle formation in autophagy and the cytoplasm-to-vacuole targeting (CVT) pathway; binds PtdIns(3,5)P2, PI3P and PI4P; WD-40 repeat containing protein and PROPPIN family member; relocalizes from the vacuole to cytoplasm upon DNA replication stress; mammalian homologs include: WIPI1, WIPI2, WIPI3 and WIPI4/WDR45; mutations in human WDR45 cause static encephalopathy of childhood with neurodegeneration in adulthood (SENDA)
External sources Open in SGD external link
Open in KEGG external link
Gene Sequence
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Promoter Sequence
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>ATG18 YFR021W
ATATATGGTGATATGAATGGCCACCATTATTCTGTTTAATATCAAGTAATGGACAAAACC
TTTCTTTTCCTGATTGATGTAGTTCACTGTAACCTTCTTGTTCGTGGGCACACTTACTTA
GATATTTCCTTGCGCAGTTATTATACTGAATTTAGAGAAGCGACGCAATATTTCTACGTG
ATATCTATAAAAAAGAATACTTCACTTATGCAAGCATCGCCTGGCTGTAATCTTTGCTTC
AGACCATCTGACACATGTACACAGTAACACATAGCGAGCTATGAAAAGATGATGGTGAGT
TCGTGGTATGGCTACGTAGAAGATATGCGATTCATGCACTACCACCGCTTAACGTAGTTA
TCCGAATGCATAAATTAGACTAGTATGTGACAACGCTAAACATGCGTTCCCCAGAACCAC
CTGCGGTTGTTGAGAGGAATAGGTTTTGCGCTTGTCTATGGACACTTTCTTGAACTCAAT
CCAACTGAGCAATACTTAACAATATTGCGATTACTTGTTCTTACATAAAGAGTAAGAAAT
ACTTGCGAAATAAACGGTAATCAATCAAATTTAGGGTCATAAGTTGTATTCGCACAATAT
GCATAAGCACTGACTCAAGAAAGAAGATGGTTTTCGAATGGGGAGCTAGCAAAAAGAGTC
ACCCCTAAGTATAAAAACTGAATTACAAAGCTCTTCGACTACTTTCTGCAAGTAAATCAT
TCGGAAGTGCGACAATATAATGACAAAAGACGATAAGTTACTTCTATTAATTGAACTTTA
AGTATTTGGCTTTTATTTTTTTTTTTTCATTTTCTTACTCGCGCTTTTCTTTATTAAGGG
CTTTCTCAATTAGATGTTAATAATGTCATAAGGCATCGTTATTCCGCTTTATATTGGTAA
CTCAGCAGTGGTCATTGCCTTCGTTCACGACCCTCCCTTATTAATCAGTTAGTAATAGTG
TTCCAGTTAACTCTGTATCCTTTTCTTCTTCGGCCTGACA
Chr coordinates Chr VI from 194812-196314
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