S.cerevisiae - Yeastract

Locus Information

Standard Name	ATG18
Systematic Name	YFR021W
Alias	AUT10, CVT18, NMR1, SVP1
Strain	S288c
Description	Phosphoinositide binding protein; required for vesicle formation in autophagy and the cytoplasm-to-vacuole targeting (CVT) pathway; binds PtdIns(3,5)P2, PI3P and PI4P; WD-40 repeat containing protein and PROPPIN family member; relocalizes from the vacuole to cytoplasm upon DNA replication stress; mammalian homologs include: WIPI1, WIPI2, WIPI3 and WIPI4/WDR45; mutations in human WDR45 cause static encephalopathy of childhood with neurodegeneration in adulthood (SENDA)
External sources	Open in SGD Open in KEGG

Gene Sequence Download FASTA View Seq	Sequence hidden
Promoter Sequence Download FASTA	>ATG18 YFR021W ATATATGGTGATATGAATGGCCACCATTATTCTGTTTAATATCAAGTAATGGACAAAACC TTTCTTTTCCTGATTGATGTAGTTCACTGTAACCTTCTTGTTCGTGGGCACACTTACTTA GATATTTCCTTGCGCAGTTATTATACTGAATTTAGAGAAGCGACGCAATATTTCTACGTG ATATCTATAAAAAAGAATACTTCACTTATGCAAGCATCGCCTGGCTGTAATCTTTGCTTC AGACCATCTGACACATGTACACAGTAACACATAGCGAGCTATGAAAAGATGATGGTGAGT TCGTGGTATGGCTACGTAGAAGATATGCGATTCATGCACTACCACCGCTTAACGTAGTTA TCCGAATGCATAAATTAGACTAGTATGTGACAACGCTAAACATGCGTTCCCCAGAACCAC CTGCGGTTGTTGAGAGGAATAGGTTTTGCGCTTGTCTATGGACACTTTCTTGAACTCAAT CCAACTGAGCAATACTTAACAATATTGCGATTACTTGTTCTTACATAAAGAGTAAGAAAT ACTTGCGAAATAAACGGTAATCAATCAAATTTAGGGTCATAAGTTGTATTCGCACAATAT GCATAAGCACTGACTCAAGAAAGAAGATGGTTTTCGAATGGGGAGCTAGCAAAAAGAGTC ACCCCTAAGTATAAAAACTGAATTACAAAGCTCTTCGACTACTTTCTGCAAGTAAATCAT TCGGAAGTGCGACAATATAATGACAAAAGACGATAAGTTACTTCTATTAATTGAACTTTA AGTATTTGGCTTTTATTTTTTTTTTTTCATTTTCTTACTCGCGCTTTTCTTTATTAAGGG CTTTCTCAATTAGATGTTAATAATGTCATAAGGCATCGTTATTCCGCTTTATATTGGTAA CTCAGCAGTGGTCATTGCCTTCGTTCACGACCCTCCCTTATTAATCAGTTAGTAATAGTG TTCCAGTTAACTCTGTATCCTTTTCTTCTTCGGCCTGACA
Chr coordinates	Chr VI from 194812-196314