Locus Information
Locus Info
Protein Info
GO Info
Orthologs
Standard Name
ATG18 Systematic Name
YFR021W Alias
AUT10, CVT18, NMR1, SVP1 Strain
S288c Description
Phosphoinositide binding protein; required for vesicle formation in autophagy and the cytoplasm-to-vacuole targeting (CVT) pathway; binds PtdIns(3,5)P2, PI3P and PI4P; WD-40 repeat containing protein and PROPPIN family member; relocalizes from the vacuole to cytoplasm upon DNA replication stress; mammalian homologs include: WIPI1, WIPI2, WIPI3 and WIPI4/WDR45; mutations in human WDR45 cause static encephalopathy of childhood with neurodegeneration in adulthood (SENDA) External sources
Open in SGD
Open in KEGG
Gene Sequence
Download FASTA Hide Seq
>ATG18 YFR021W
ATGTCTGATTCATCACCTACTATCAACTTTATTAATTTCAATCAAACCGGAACGTGTATT
TCCCTTGGAACGTCGAAAGGTTTCAAAATATTCAATTGTGAGCCCTTCGGAAAATTTTAT
TCAGAGGACAGTGGGGGCTATGCTATCGTCGAGATGTTGTTCTCCACCTCGTTACTAGCC
CTCGTTGGGATAGGCGATCAACCTGCGCTTTCACCAAGGAGATTGCGTATAATCAACACA
AAAAAACATTCTATTATCTGTGAGGTGACTTTCCCTACTTCTATTCTGAGTGTGAAAATG
AATAAGTCTCGATTGGTGGTACTTTTACAAGAGCAGATTTATATTTATGATATCAACACC
ATGAGACTATTGCATACTATAGAAACAAACCCTAACCCACGTGGCCTTATGGCTATGTCT
CCTTCGGTAGCCAACAGCTATTTAGTGTATCCATCACCACCAAAAGTTATTAACTCCGAA
ATTAAAGCTCATGCCACCACAAACAATATCACATTGTCAGTTGGTGGCAACACAGAGACC
AGTTTCAAGAGAGATCAGCAAGATGCTGGCCATAGTGACATTAGCGACTTGGATCAGTAT
TCGAGCTTTACTAAGAGGGATGATGCGGATCCAACAAGCAGTAACGGCGGTAACAGCAGT
ATAATAAAGAATGGTGATGTGATCGTATTCAACTTGGAAACATTACAGCCAACCATGGTC
ATCGAAGCTCATAAGGGCGAGATTGCTGCAATGGCAATTAGTTTTGATGGGACACTAATG
GCTACCGCCTCTGATAAAGGTACTATCATCAGGGTCTTTGACATTGAAACGGGTGATAAG
ATCTACCAATTCAGGAGAGGGACGTACGCGACAAGAATTTACTCCATATCATTCAGTGAA
GATAGCCAGTACTTGGCGGTTACCGGCTCTTCCAAAACCGTGCATATCTTCAAATTGGGG
CATTCAATGAGCAACAATAAACTAGACAGCGATGATAGCAACATGGAAGAAGCTGCAGCC
GATGATTCATCGCTCGATACCACCAGTATCGATGCGCTGAGTGACGAGGAAAACCCGACA
AGACTCGCAAGAGAACCATATGTGGATGCATCAAGAAAGACAATGGGTAGGATGATACGT
TACTCTTCTCAAAAGCTATCCCGAAGAGCTGCCAGAACATTGGGTCAGATTTTCCCCATC
AAAGTTACATCGTTGTTGGAATCCTCGCGCCATTTTGCGTCTTTGAAACTTCCCGTTGAA
ACCAATTCCCATGTAATGACCATATCAAGTATAGGCTCTCCAATAGATATAGACACATCC
GAGTATCCGGAACTCTTCGAAACTGGCAATTCCGCAAGTACAGAGTCCTACCATGAGCCT
GTTATGAAGATGGTCCCCATCAGGGTCGTTTCCTCGGATGGATACCTATACAACTTTGTT
ATGGACCCGGAGAGAGGCGGCGATTGCTTAATATTGTCACAGTATTCCATCTTGATGGAT
TGA Promoter Sequence
Download FASTA
>ATG18 YFR021W
ATATATGGTGATATGAATGGCCACCATTATTCTGTTTAATATCAAGTAATGGACAAAACC
TTTCTTTTCCTGATTGATGTAGTTCACTGTAACCTTCTTGTTCGTGGGCACACTTACTTA
GATATTTCCTTGCGCAGTTATTATACTGAATTTAGAGAAGCGACGCAATATTTCTACGTG
ATATCTATAAAAAAGAATACTTCACTTATGCAAGCATCGCCTGGCTGTAATCTTTGCTTC
AGACCATCTGACACATGTACACAGTAACACATAGCGAGCTATGAAAAGATGATGGTGAGT
TCGTGGTATGGCTACGTAGAAGATATGCGATTCATGCACTACCACCGCTTAACGTAGTTA
TCCGAATGCATAAATTAGACTAGTATGTGACAACGCTAAACATGCGTTCCCCAGAACCAC
CTGCGGTTGTTGAGAGGAATAGGTTTTGCGCTTGTCTATGGACACTTTCTTGAACTCAAT
CCAACTGAGCAATACTTAACAATATTGCGATTACTTGTTCTTACATAAAGAGTAAGAAAT
ACTTGCGAAATAAACGGTAATCAATCAAATTTAGGGTCATAAGTTGTATTCGCACAATAT
GCATAAGCACTGACTCAAGAAAGAAGATGGTTTTCGAATGGGGAGCTAGCAAAAAGAGTC
ACCCCTAAGTATAAAAACTGAATTACAAAGCTCTTCGACTACTTTCTGCAAGTAAATCAT
TCGGAAGTGCGACAATATAATGACAAAAGACGATAAGTTACTTCTATTAATTGAACTTTA
AGTATTTGGCTTTTATTTTTTTTTTTTCATTTTCTTACTCGCGCTTTTCTTTATTAAGGG
CTTTCTCAATTAGATGTTAATAATGTCATAAGGCATCGTTATTCCGCTTTATATTGGTAA
CTCAGCAGTGGTCATTGCCTTCGTTCACGACCCTCCCTTATTAATCAGTTAGTAATAGTG
TTCCAGTTAACTCTGTATCCTTTTCTTCTTCGGCCTGACA
Chr coordinates
Chr VI from 194812-196314
