Locus Information
Locus Info
Protein Info
GO Info
Orthologs
Metabolism
Standard Name
HEM2
Systematic Name
YGL040C
Alias
OLE4, SLU1
Strain
S288c
Description
Aminolevulinate dehydratase; a homo-octameric enzyme, catalyzes the conversion of 5-aminolevulinate to porphobilinogen, the second step in heme biosynthesis; enzymatic activity is zinc-dependent; localizes to the cytoplasm and nucleus; human homolog ALAD can complement yeast hem2 mutant
External sources
Open in SGD
Open in KEGG
Gene Sequence
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Sequence hidden
Promoter Sequence
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>HEM2 YGL040C
GATTCTATTGAAACGACACCATACAGCTCATACGAGTCCGGTGTACTGGCACAGAACACA
GATGACAATACAAAAGTAAATAAATCTATCGACAGCAATTCCTATTTTCTTTTACATTTA
TATTGATTAGCTTACGATTTCTGTATTTATAGAGCGTGTAGTTACATATCCAGATACCTG
TCTTCTAGGTGAACAGTTGGTTTTCAGTTCAAAAATTATATAGGATCTTGGACGGTTAGC
TTTCCTCCTCATGATCCACTCTTTCGGGAACAAGATAAATTATTGTTTAGTTTTGATTAG
CTTTACTTTAATTCGCACAAAAAAAAGCCTGCATTGTCACGAGAACATTGAAACATATAC
AAAAAACAAATTTGAAATAGAAAACAAAGCAATTTACAGAAATGACTGCCTGGTGCTAAT
TCTTGCATATATTTTATTTTTAATTAACTAGAAATCAGCGTCAATTATAGTTTCTGGTGA
GTCAGCCAATGTCTGTAAATAAAAACAATATGCTTAAGAGGATTAACAGTGGCACAAGAG
GCAAAGAAGGGAAGAAGGCGTACACGTCCACATGAATATATAAAAAAGAAGTGTTACATC
AATTGGAACCCATCTTTCGGAACGTTTTCTATCTGCTACAAGCCTGTGTCACCGAATTAC
TTTATTGGGTCTTGTAGAGACGCCGAAATACATCATCATTCCAAGATCGACGATAAAAAT
CATCCAAAAAATTGTTGCCGAAAAAAAAATTGGAAAAGGTGAAAAAAAAATCAAAATACG
GGTAAACGAGCAATCCCTGTTCGGTGCGGTGATTGGCTTGAGGCAAGCTTCCCGCTTGAT
TTATATAAGAGTAAGGCAACCTAATAAATGCTAGCAACATCTATGCGCCACTCTATTGTC
TTTGATTTTCTTGCCCAATCAGCCAAATAAAAAAAAGTTTTACTGCTTACTCATATTATT
GCTTACTCCAGTAATTCATACCTAGAAAATTGACAAAACC
Chr coordinates
Chr VII from 420555-419527