Yeastract
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YEASTRACT+ INESC-ID IST IBB
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Locus Information

Standard Name ERG1
Systematic Name YGR175C
Strain S288c
Description Squalene epoxidase; catalyzes the epoxidation of squalene to 2,3-oxidosqualene; plays an essential role in the ergosterol-biosynthesis pathway and is the specific target of the antifungal drug terbinafine; human SQLE functionally complements the lethality of the erg1 null mutation
External sources Open in SGD external link
Open in KEGG external link
Gene Sequence
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Promoter Sequence
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>ERG1 YGR175C
GGATAAGCTGTTCACAAAATCTCTTCTCGAGTATGGGTTCGATGTGGCTATTCCAAGCAA
CGCAAGAAGGTTTTTACCAAACGATGAAGAGTTAAGAGATTCTTATAAATACGGCTCCAA
CGTTGGAGGTTCGCATTACGCCTATCTAATCTCCTCATTCGACATTCCCGAAGGTGACAA
TGACAAGTTTTGGAGTCTTGTCGAATACTACTATGACCGCTTTTTAGAATCGTACGACAA
CGGTGACCACTTGATTGGTCTGGGGGTCCTACAACTTGATTTTATCGTTGAAAACAAGAA
TATAGACAGCCTTCTTGCCAACTCTTATTTGCACCAGCAAAGAGGCGGTGCAATCATCAG
TAATACAGGACTTGTCTCGCAAGATACGACCAAGCCGTACTACGTTCGGGATTTAATCTT
CTCGCAGTCTGCAGGCGCCTTGAGATTTGCGTTCGGCCTAAACGTTTGCTCCACAAACGT
GAATGGTATGAACATGGACATGAGCGTGGTTCAGGGCACTCTACGGGATCGTGGCGAATG
GGAATCGTTCTGCAAGCTCTTCTACCAAACCATCGGCGAATTTGCGTCGCTTTAATGCGA
TACTGCCGTAGCGGGCCTTCGTATAGCTCGGCCGAGCTCGTACAAAAGGCAAGCAGTGTA
TCGGACAGAGCTGATATAACACAATACGCTCGTAGTCGATGCATGCCGTGGCTGCTCTCG
GTCGGGTATAAGTCTTAGACAATAGTCTTACCTCGCATGTATAATAAATCTTTTGTATTT
AATCTATTATATGTTTCTATGCTTTTTTTTCCTATTGTTGTTTGCTTTTCCTTTTCCTTA
TTTCTTTCTAGCTTCTAATTTTCTTTCTTTTTTTTTTTTTTTTCATTGAAAATTATATAT
ATATATATATATCAGAACAATTGTCCAGTATTGAACAATACAGGTTATTTCGAACAATTG
AAAAAAAAAAATCACAGAAAAACATATCGAGAAAAGGGTC
Chr coordinates Chr VII from 848423-846933
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