Yeastract
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YEASTRACT+ INESC-ID IST IBB
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Locus Information

Standard Name ERG11
Systematic Name YHR007C
Alias CYP51
Strain S288c
Description Lanosterol 14-alpha-demethylase; catalyzes C-14 demethylation of lanosterol to form 4,4''-dimethyl cholesta-8,14,24-triene-3-beta-ol in ergosterol biosynthesis pathway; transcriptionally down-regulated when ergosterol is in excess; member of cytochrome P450 family; associated and coordinately regulated with the P450 reductase Ncp1p; human CYP51A1 functionally complements the lethality of the erg11 null mutation
External sources Open in SGD external link
Open in KEGG external link
Gene Sequence
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Promoter Sequence
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>ERG11 YHR007C
CTTGTTCTCTCTCGCTTCCTACGTTACTCGCGCCTGTGCACTACATTCCCACCAGATTAA
CTCACCACCAGGCAGAGAACCAATTGTTCTTGTTATTGTTCCAACCGATAATTGTAAAGC
CATTAAGGTCGTAAACGACTGCTTACTCAGGGAGATCTCCGAAAACGGCAATTGCTGTGC
ACCGTGCGACGTTATGATCGCCGCCTGTCCCGTACAGACGAACAATTGCAACAATGGGCG
GTTGTTTAGAGAGGTTTTGTGCCGCGCCCGGGAATTACCGGGGGCACAGCAAAATACGAA
ATTTCCGGCAAAATGTCTCTGTACGAAAATGAGGCCAGCCTTTATTCCCGACTAAGCCGT
ACGATTATAGTAATGTCACACGAAGTGGATACTATACGAGCAGCGCACATACAATGTGCG
TGCAAGATTTGCCGGGTTGGACAATCTTAAAGGCCGATAATCCACGAAAAACGAGACAAA
CGAAGCGCTGGCCCTAAACGAAACGAAACGAAACTAAGATTTCAAGATAATCGCTTTTCA
GATGACAATAGTCTCTTGCAGAACACAATAAGTGTGGTAGGTATCTTGCAGGAGACATCG
ATTTTATGCCTGAATTTTTTTTTTTTCTTGGTATGAGCACATCCTATTGTGCATCTCCAC
GAGTTAACGACGTTTACGTACTCGCATGTATTCGAAAAGCCTCTAAAAATTGCCCTCCAT
GTGTATTCATTATATAAGATAGCGTATTTTCCCTTAGTTTTCTTATTCCCTCTTAATTCT
CTCTTTCAATGTCTTTTTTTTTTTCCCTTTTCCTTTTTCCCTTTTCGTTATTGGTAAATT
ATTTATAAAAAGATTGATAAGCAGTATCGTTCAGCGTGTGTATTTTCGATAGGAAGTAAT
AATTTTTCATTATATTAATTAATAGTTTCCAGAAAAAATTTTTTTTCCTTCACAATTGCA
GCAGGCTTGAATAGAAACAGAACAAACGAGTAATACAAGG
Chr coordinates Chr VIII from 121683-120091
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