Locus Information
Locus Info
Protein Info
GO Info
Orthologs
Standard Name
IRE1
Systematic Name
YHR079C
Alias
ERN1
Strain
S288c
Description
Serine-threonine kinase and endoribonuclease; transmembrane protein that mediates the unfolded protein response (UPR) by regulating Hac1p synthesis through HAC1 mRNA splicing; role in homeostatic adaptation to ER stress; Kar2p binds inactive Ire1p and releases from it upon ER stress
External sources
Open in SGD
Open in KEGG
Gene Sequence
Download FASTA
View Seq
Sequence hidden
Promoter Sequence
Download FASTA
>IRE1 YHR079C
GTCTTATCCTTGCCATAAACAGAAGACAACTTGCAAGTATGAACTATTTGGAAACACAGT
TAAATAAAAAGCAAAAACAGATACAGGAATACGAAAGTATGAATGGCAACCTGATAAAGA
TGTTTGAGCAATTGTCTAAAGAAAAGAAAAAGTATGTAGCTATTTTTTCCAGTCGGCAAA
AATCGGTATAACAAACAAAAAATATTTAGTTTCTGTTATTAACAGAACTTGTCAAAGTGA
TGAGACACCAAAAAAAATTTCCTCGACGTACATTAAAGAGTTAAAGGAGTACAACGAATT
GAGAGATGCCGGTTTAAGGTTGGCCCAAATAATTGCTGATGAAAAGCAATGCAAAATTAA
GGATGTTTTTGAAGAGATCGGTTATTCAATGAAGGACTAATGGGCTTTTAGGGACAGTTC
TATTCTTCCAACGTGCGAAGCGTTCCAATGAAACTCTGCTGCGCGCTGAAAACTATATAA
AAAAAAAAAAAGATAAAATTACAAAGAAGTAATGAACTTAAATGCTATTATACAGTTACT
AATTAAGCTGCGTAGTGTGAAATATATTGATAGTTGTAGTTTTGAGGTTTTATTACCCTC
TGTTATATAATAGGTTTTCGCTATTTTATTGCCGAAAATCAAGACGGAGCGTAAGCCTCT
TCGGGCAATACCTTCGACTATTCCAACAATAAAATTTAAAAAAAGAGATTAATCACATAG
TAACAAGAAATAAACGAAAAACATATCATAGGAGATCAATGAGCCAACTTCACATAAACT
AACAGTGAAAAGTCTATAACAATATTAATTTTACACAATTAAATCTACACTATAACTGGC
ACTGTTAATAATCGGTAATCTGCTAAGTAACTTTTTTTTCTCATTCACAAAGCATCGTTT
TCCTCTTCCCCACGTCCATTATCACTTTTCTCCATATCACCCTTCATACACATTAAAAAA
ACAGCATATCTGAGGAATTAATATTTTAGCACTTTGAAAA
Chr coordinates
Chr VIII from 261591-258244