Yeastract
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YEASTRACT+ INESC-ID IST IBB
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Locus Information

Standard Name NSG1
Systematic Name YHR133C
Strain S288c
Description Protein involved in regulation of sterol biosynthesis; specifically stabilizes Hmg2p, one of two HMG-CoA isoenzymes that catalyze the rate-limiting step in sterol biosynthesis; forms foci at the nuclear periphery upon DNA replication stress; relocalizes to the cytosol in response to hypoxia; homolog of mammalian INSIG proteins; NSG1 has a paralog, NSG2, that arose from the whole genome duplication
External sources Open in SGD external link
Open in KEGG external link
Gene Sequence
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Promoter Sequence
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>NSG1 YHR133C
ATACTTATAATTTTCGAGTTCTTCGCTGTGGACAAGAGATTAAGTGAGATCAATAACTTC
GATAAGAGTATCTCCCGGGAGTACCTCGTCATCATCATCAAGGATTACAACTTCTAAGGA
GCTGCTAATATTATCACTTATTATTTGATCTTTGTTATTCTTCGTCTCTCCGCACCAGCG
ATCATCTCTATATCTCCTTTCGGCTGCAAAAGCCGCCAACTCTCTCGGGGAATTACCTCT
ATCTATAGATGATATACCCTCTGGATGCAAACTCCCTAACTTCACACCTTTGCCCCTTTT
TCTCACTATCCCTGTGTTAGTACTTATTCCTGTCATAGGATATCTATTTGAACGTAAGTT
TGCTCTTCCACCGAGACGTTGACCGTTCCCCAAAAATGTGTCGTACAAACCTCTTTGTTC
AATAACCCATTGCCTTCCAATCAACTCATCTAGCTTATTGTAGAACTTTTTGTCGTGTGG
ACCGAATAAATTGTGAGTTAATTCGTGCAGCATGGTGCCCATTATACACTCCATGGGTAA
AAATTGGAACTCATCCGTGGAGCATCTTAACCGTAACATTATCTTAGATCCATGGTTGAC
GTTCATTCCCAGGAGTCTTTGATCACGTGGGTAAAACTCCACCAAGTTGGTCACTTTGAA
GTGATTTTCCTTCATTAGATAGGAAACTTTATGTGCGATTTCCTTTATTAAATTTAGCGC
ATCTTCCTTATTGGGCTTACTTTGCAAAACAGCCACTTTTTGAATGTGCGGGTTCTTGTG
AGGGATTCTCTGGGAGCCCGCCATATCATGGTATTTTGCCGATGGGCTTTTTATTCCTTC
TGTCTTCATTAATCAATCTCTCTTATTTAGAATATCTTCAAAATATGCGTTGTTACAAAA
TACAGCGCAAAAGAAAAAGTGTCAAAATTTCTTCACCAAACTCACCTTTTGGTATTCAGA
GCAAGTGAGAAAAAAAAAATTTAAACAGAGGAGGTTACTA
Chr coordinates Chr VIII from 371597-370722
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