Yeastract
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YEASTRACT+ INESC-ID IST IBB
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Locus Information

Standard Name RTT107
Systematic Name YHR154W
Alias ESC4
Strain S288c
Description BRCA1 C-terminal domain protein needed for recovery from DNA damage; implicated in Mms22-dependent DNA repair during S phase; involved in recruiting SMC5/6 complex to double-strand breaks; DNA damage induces phosphorylation by Mec1p at one or more SQ/TQ motifs; interacts with Mms22p and Slx4p; has four BRCT domains; has a role in regulation of Ty1 transposition; relative distribution to nuclear foci increases upon DNA replication stress
External sources Open in SGD external link
Open in KEGG external link
Gene Sequence
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Promoter Sequence
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>RTT107 YHR154W
CTTTCTAGTCATCCAAAAATAGCCAAATGCTACACTAAACCAATAAGCAAACGAGTACAT
AAAGAATAAGTAAATAATAATTCAACAATACCTGATTTTTTTTTTCTTACATTTTTTTTA
TTATTCATTAAAAGCAACCACCAAGCTTTCCAAATTATGAAACCTTGATAAAATGGCTTC
AAAATCTTGATCTGGAATTCCGTTTTTTTTGAAGAGGTCGAAAATTATTTGCTTGATTAG
AATTTCAAAATCAATAAACTCGTCCATATCCACGCTGTTCCGTGTCAAACGCTGGTTAGC
TTTAAAAGCTAGAAAATATTGATTGTTTTCAACATATCGACTTCTGTCTACTGGTGTAAC
CTCTGTAATAAAGTAGCGGGCACCCGTTTTCGATGGTCCATTTATTAGATCTAGTGACCT
CTCCAATAAGATATCCCAATAAGCTATTGAGAATTTCAAGCGCGTGAAATTCAAATTTAT
CATCAGAGAACGATGTGCGGGAACTCCAGGGCTTTTCTGTATTTTCTCATAGACATTATT
TATCAGTAATTGCAGCTGTGTAACAATAAAATTGACGCCACTTTCTTCGTCTTGTAGCTC
CTCGTTAAGCTGCGAAATTAACCTGCTCGTATTCACAGTAACACACTTAACCACAGAATG
TTCTTCGACATTAGAAATCTCTTGTATTTTTTGTACATCCCAAAAGAATTCAGACATTTC
TATTGAACCATTCCAGAAATGTTGTTCCAGAAGTTTATTCTCTTGAACCTTTACACTATT
TCGTATTTTCTCGGTTTTAGCCGCCCACTTTTCACGCGTTAACAGGGTAAGCTATATCAG
ATGTGACTTTTCTTTTTCACTCATCTAATGTTGTTTTTCGCGTCACATTTTTTGCCAATA
AATAAATACATCACAATGTTCTATATTGTATATTCAATGGAAGTCATTAGGTTATTGGGC
AAGATTTCAAGGAGGTAGCATACTGGTAAATATACGATCC
Chr coordinates Chr VIII from 402966-406178
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