Yeastract
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YEASTRACT+ INESC-ID IST IBB
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Locus Information

Standard Name TIF2
Systematic Name YJL138C
Alias eIF4A
Strain S288c
Description Translation initiation factor eIF4A; DEAD-box RNA helicase that couples ATPase activity to mRNA binding and unwinding; ATP hydrolysis accelerates the recruitment of mRNA during 48S preinitiation complex (PIC) assembly; ATPase activity stimulated by either eIF4G1 or by the PIC in an eIF3g and eIFGi subunit-dependent manner, independent of eIF4E and eIF4G; subunit of the mRNA cap-binding protein complex (eIF4F) with eIF4E and eIF4G; protein abundance increases in response to DNA replication stress
External sources Open in SGD external link
Open in KEGG external link
Gene Sequence
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Promoter Sequence
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>TIF2 YJL138C
CTGCGGTTCCAGACATCGGATGGCCTGACATGTTCAACACCGGTGTACTACTACTAATTC
CTGATTTAGATATGGCAACAAGTTTACAAGATTTTTTGATTAAAACTGTATCGATTGATG
GTGCTGATCAAGGAATCTTCAATCAATTTTTTAATCCTATTTGCAACTACAGCAAAGAGG
TTTTGCATAAGGTGTCTCCACTCATGGAATGGATACGCCTCCCCTTCACCTACAACGTAA
CCATGCCCAACTACGGATACCAGTCTTCACCAGCCATGAATTTTTTCCAACAACACATCA
GACTTATTCACTTCATTGGAACGTTTAAGCCATGGTCCCGTAATACAACTGACTATGACG
ACCACTATTACCAGCTGTGGAGAAGTACACAGCGTGAACTTTATAGTGAATGCCACTTAA
GTAACTACTTCACACACTTGCAATTGGGCAATATTGAAACAGAGACAAATTTTTACCACG
AACCTCCTTGTCTTCAAGACCTGTTGAATCATGGTAAAAGAGAAAATCAAAAGCACGTTG
ACCTGGATATAACCTCAGTAGATCGAAATGCTTCGCAGAAGAGTACTGCAGAGAAACATG
ATATTGAGAAACCGACATCTAAGCCGCAATCTGCTTTTAAATTTGATTGGGAGTCTACGG
ATTATTTAGACCGCGTCCAAAGAGCATTCCCAAAGCCTGATACCTGATGCCATCCCTCTA
CCTCTTAGCTATCAATCATTCAACTAAACTACTACATAGTATACATTAGCTGTACAGTCG
TCACATCAGACGAATACAAAAGGCCGGGTGAAAGCGTTGATTTTGCGTACCTTTTTCTTT
TTTTCGAAATTTTTTTATTTTTTTTTCAGCATCATATATAAAAGAAATCTCATCTCAAGG
AGAAGGAAACAGCAGATCCCAATACACATAGTAGGAAAAAAAAAGGTTCGCTAAACAAAG
GACTGGTGTGTACAAGAAACTAATAAATAGTAATTGCAAT
Chr coordinates Chr X from 154691-153504
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