Locus Information
Locus Info
Protein Info
GO Info
Orthologs
Metabolism
Standard Name
BNA2 Systematic Name
YJR078W Strain
S288c Description
Tryptophan 2,3-dioxygenase or indoleamine 2,3-dioxygenase; required for de novo biosynthesis of NAD+ from tryptophan via kynurenine; up-regulated by telomere uncapping, and interacts genetically with capping gene CDC13; overexpression reduces lipid droplet accumulation by skewing glycolytic flux towards biosynthesis of shikimate, aromatic amino acids, and NAD+ during aging and extends lifespan; regulated by Hst1p and Aftp External sources
Open in SGD
Open in KEGG
Gene Sequence
Download FASTA View Seq
Sequence hidden Promoter Sequence
Download FASTA
>BNA2 YJR078W
AGGCGGTATCGTAACCCAAGTTGTCAATGAAGAACTTCTTGAACACTTCGTAACCACCGA
ACTTGAAGGCACCTTGGATAGAGTAACCCAACAAAGTAGGACCAAACCCGGTCAACAACG
CACCAGCACCTTCTCCGGCGATGATTTGCTTGAAAGAGCCGACCATACCCTTGTTGTACA
CGGTAGGTTCCAGTTGGATTCTCGTCTTAACGACATCGATCGGGACCATACTGGAGTGAG
TCGACCCGCACCCTATGGCGCCGGCTAGGGCGAATTTCATGTAGTCAGAGACAGAGTACT
GTGGAATAGCAGGAGCAGCAGACACAGACATGGTGAGATGAGACTTTTTGATCTTTGTAG
TTCTTCTTCTTGCAGATCACTCTGTTCTTTGCGATGGTTCTTGTAGATAAAAAGATCGGG
AGGATGGATCGCACTTAAAAATCTTCTCGAAACGGGCCGCGGCCGGGCATGGGACCCGTT
CTCGACGCTGATTGGCTAACGATGGTTGGGCAGAGTCTCAGCTGCTGCTTGCTCACATTC
GACAAAAGACTAGAGGAAAGCAGTACCATGCTGCGATACTGTTGCATCGCAGCATTCCGC
TGTCCAAAAACAATACCTGTTGTATTGTTTGAGGCTGGCAGGCGCTTGGGTAGAAACAAC
ACCCGATACTGGTGACAGGGCTATCTATAAATATTAAAACTTGACTCCGCAATTCGTCGT
AAACTGCCTTAACCATCGTAATGGACGCCGTGCAAATGCTTCGACTTTTCCCAGTAGTCA
GGCATTGCGCCAGACACTTGTGCTGCTTAATTGTCGTAATGAAAACATATCGGTAGCGGC
CTTTTTTTATTTTTTTTCTCTATGGGCTGACGCTGTCACTTTTCAACGTCGCTCCGAGGC
AAAAAAGCCACCGTCAGAAATAATTACTGTCACACACACTAGATGTCCATGTATCTTTAG
CATATATAAAGCGAAAATAAAAGAAAGAGTCAACGCCGAT
Chr coordinates
Chr X from 578860-580221
