Locus Information
Locus Info
Protein Info
GO Info
Orthologs
Standard Name
YPF1 Systematic Name
YKL100C Strain
S288c Description
Intramembrane aspartyl protease of the perinuclear ER membrane; acts in a branch of ER-associated degradation (ERAD) that degrades functional proteins rather than misfolded proteins; regulates abundance of high-affinity plasma membrane transporters, such as Ctr1p and Zrt1p, during the starvation response; has a presenilin fold; member of the GxGD family of intramembrane proteases; closest human homolog is signal peptide peptidase (SPP) External sources
Open in SGD
Open in KEGG
Gene Sequence
Download FASTA View Seq
Sequence hidden Promoter Sequence
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>YPF1 YKL100C
GTACATGATGTTCAGAAAAAGCAGCATAGAGAACGTTCTCAGCTAACTAGCCGTTCCAGA
TATGGGTTTTTAGAAAAGCATAAAGACTATGTGAAACGTGCTCAAGACTTCCACAGGAAG
CAGTCCACTTTGAAAGTCCTCAGAGAAAAAGCAAAAGAGAGAAATCCAGATGAATACTAC
CATGCTATGCATTCAAGGAAGACAGATGCAAAAGGACTGCTGATCAGCTCACGTCACGGT
GACGAAGAAGACGAATCGCTTTCCATGGATCAAGTTAAATTACTCAAAACGCAAGATAGT
AATTATGTGAGGACGCTGAGGCAAATAGAGCTGAAAAAGCTGGAGAAAGGAGCGAAACAG
TTGATGTTCAAAAGCAGTGGGAATCATACAATATTCGTCGATTCCCGAGAGAAGATGAAC
GAATTCACCCCAGAGAAGTTTTTCAATACCACCTCCGAGATGGTGAATAGATCTGAAAAT
AGATTAACTAAGGACCAATTAGCCCAAGATATTTCAAACAATAGGAACGCTTCATCAATA
ATGCCAAAGGAATCATTAGACAAAAAGAAATTGAAAAAGTTCAAGCAAGTCAAGCAGCAC
TTACAGAGGGAAACTCAATTGAAACAGGTCCAACAAAGAATGGATGCTCAAAGAGAATTG
TTGAAGAAGGGTTCCAAGAAAAAAATCGTAGACTCTTCAGGAAAAATTTCATTTAAATGG
AAGAAACAACGGAAACGTTAGATTTTTACCATCTATATAGTATATATAAGTGAATCAGGC
AGACGTTCCGTAATCCTTCTTTTCATGTTTTATAGGATTACGTTTATAAAAAGTATTCAC
TTTTCTTAAGTGTCTTTTGCGCCATCAAAAAAAAAAGGATTTTGAGGCACCGGAAAAAAA
AGAACCCCTCTCCGAATGGGAGTATTTAGGACAAGATTTGTAAAGTGCTCCCTTTTTGAG
CAATACTACAGATCTATAATGGGGAACAAACTCATACACG
Chr coordinates
Chr XI from 255460-253697
