Yeastract
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YEASTRACT+ INESC-ID IST IBB
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Locus Information

Standard Name YPK1
Systematic Name YKL126W
Alias SLI2
Strain S288c
Description S/T protein kinase; phosphorylates, downregulates flippase activator Fpk1p; inactivates Orm1p and Orm2p by phosphorylation in response to compromised sphingolipid synthesis; involved in the TORC-dependent phosphorylation of ribosomal proteins Rps6a/b (S6); mutations affect receptor-mediated endocytosis and sphingolipid-mediated and cell integrity signaling pathways; human homolog SGK1 can complement a null mutant and the inviability of a ypk1 ypk2 double mutant
External sources Open in SGD external link
Open in KEGG external link
Gene Sequence
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Promoter Sequence
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>YPK1 YKL126W
CAGAGAAAAGGACGGTCTATGGGCCATTATTGCTTGGTTAAATATCTTGGCTATCTACCA
TAGGCGTAACCCTGAAAAGGAAGCTTCGATCAAAACTATTCAGGACGAATTTTGGAACGA
GTATGGCCGTACTTTCTTCACAAGATACGATTACGAACATATCGAATGCGAGCAGGCCGA
AAAAGTTGTAGCTCTTTTGAGTGAATTTGTATCAAGGCCAAACGTTTGTGGCTCCCACTT
CCCAGCTGATGAGTCTTTAACCGTTATCGATTGTGGTGATTTTTCGTATAGAGATCTAGA
TGGCTCCATCTCTGAAAATCAAGGCCTTTTCGTAAAGTTTTCGAATGGGACTAAATTTGT
TTTGAGGTTATCCGGCACAGGCAGTTCTGGTGCAACAATAAGATTATACGTAGAAAAGTA
TACTGATAAAAAGGAGAACTATGGCCAAACAGCTGACGTCTTCTTGAAACCCGTCATCAA
CTCCATTGTAAAATTCTTAAGATTTAAAGAAATTTTAGGAACAGACGAACCAACAGTCCG
CACATAGAATTATTGGTCTTGAACAAGCACTAATTTTCCAAAGATGTTTTAACTGATCTT
AATTTATATGTAGAGGATATATGTAGTATATCTATTTTTTGCTGATTGACTTATCAATTA
GCTTCATAATACAACATTGTTTTTGTTTTTCGTTACTCGCGACTTTCTTCGCGGCAGAGC
CGCGCTACAGGAAAACAAGATCAAAACATGCCCCTATTGGAAGGCTTAAAAAATGCTTAT
CCCGAACGAGCCAACGGTAATCAACACTATCGTCATACCAACAACAGTTGAGTTATTTTT
CGCTCCCATACTTTTTAGAATTGGTTTGTTTGTGTTTGGTTAAATTTCAAAGCCTTTATA
TTCTTTGATATAGATTACTCTACAATTTCTTTGTATACAGCGGGAAATTGACACTTCAAA
GTTCCTCTCATATCAACAAACATTAATACAGTTCCTGAAA
Chr coordinates Chr XI from 205707-207749
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