Locus Information
Locus Info
Protein Info
GO Info
Orthologs
Standard Name
GCN3 Systematic Name
YKR026C Alias
AAS2 Strain
S288c Description
Alpha subunit of translation initiation factor eIF2B; guanine-nucleotide exchange factor for eIF2; activity regulated by phosphorylated eIF2; positive regulator of GCN4 expression; mutations in human ortholog EIF2B2 cause fatal brain disease childhood ataxia with central nervous system hypomyelination (CACH); human ortholog EIF2B1 can complement yeast null mutant External sources
Open in SGD
Open in KEGG
Gene Sequence
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Sequence hidden Promoter Sequence
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>GCN3 YKR026C
ATGTTATTGTCTCGTTTTTTTACTTTATATGCTTATTCTTTATCTTGTTACGTTATCAAT
GCTTGCATTTCAGCTTCTATTATATTTAATAACCGTTTCTCATTCTTAATGTCATCTTCT
TACACTGTGTATGAGAACATACTGCTAATTTGTGTGCTAGTGCATAGATGGTAGTTAATT
CTTATTCAGACAAAAAGTTTTAGTATCTGATCTGTTGTTAAACATGTTAGATAAGTATTT
TTTGGAATAAAGATCCACTATCGTATATTGGCTAGCGGTCGTGACACTAATATGTTATTA
CATACTGCATAAATAGAATACACAAATCGTGAGGTACAGTCATCCAATGTTGTGGAAGTC
GATACTCAAGACCTAAAGAAAAATAAAATTTCTGAATGAAAAACATAACGATAGTAAAAA
TGAGCGGTATGTTATGACATAGGAGATAGAAGAACAAAACTGATCTGATCAAATTATTTT
AAGAATATTTTACTAGTATGTTTACTACATGACAATCTGCAGCAGTGCCAGCTACATGGT
GATCTCTCCAAAACAGACCAAACAATTTGCGCTTGTATTGCTTTTCAAAATAAAACTAAA
CATATGTAATTGTGCTTACAAGAATTGCTAGCTATATCTTATGTTGGTAATAGATAACGA
TTAGTAATACCTTTTATGAGAAAGAATAAGGAGGCAATGCCATCATTTTCGCCACATTAA
GAGTGCACGACTCTATCCAGGGAATTTGATACAACACAGCAACATTGTCGCCATATTTAA
AGCTTTCTACATAGCATAATGTTTTTTTTTTTTTACAATAGATAAATTTCATCCGGAAGA
AAAATGAAAAAAAAATGAAAAAATTGGTGAAGTTTATGGTGTAAAATGAGAATCATACTG
CTCAAATAGTGACAAAGCCATCATTAATCATAGATTTCTTCATAGTAATTGATAGAAAGA
ATTTTAAAAGTCCTACGTATACCAGAAATCGAGAGGAAGG
Chr coordinates
Chr XI from 489655-488738
