Yeastract
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YEASTRACT+ INESC-ID IST IBB
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Locus Information

Standard Name LAS1
Systematic Name YKR063C
Strain S288c
Description Endonuclease involved in pre-rRNA processing at both ends of ITS2; functions with Grc3p in a conserved mechanism to cleave pre-rRNA at a specific site during rRNA processing and ribosome biogenesis; may coordinate the action of the Rat1p-Rai1p exoRNAse; required for the G1/S cell cycle transition; human ortholog is Las1L; mutants require the SSD1-v allele for viability
External sources Open in SGD external link
Open in KEGG external link
Gene Sequence
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Promoter Sequence
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>LAS1 YKR063C
CCTTTGCTAATATAGTTTCTGAGCTGAATTTTTTAGCATTATTTTCTCTGTATTGAGCGA
ATTTGTTAAACAATGATTTGTGAATAGTCTGATGCATGCGGAAGTTATTGCCCTTACCAA
CAACATCATCGCTAATGTGGCGTTCGTCATCAGCATCGAAAGTGGATAAAGCTTCGAAAG
ATTTAGGCAAGCTTCCATTTTTCACATTATTGCCGTTGCTTCCCAATTTATCCATCATTT
TTTTGATTGCGATACTTCTAAATGTTACCATTGCTTGGAGATAGGGGTCGCGATTTTCAA
TTGCTCTATCCGTGAACAGACCAAATAAATTATCAGCAGACCTTTTGGTCTCTAAATAAA
ACCCATTAGGGATGAGGTCAATAAAAAATGGAGTTTCTTCATGAATTGGTAGATAATAAA
GTGATGATTGATTTTCAAGTTCTCGTACTCTTTGCCAGTGATCTTCGTCTTGTCTTGTCT
GTGACGATCTTCTTTTCTTAATGAAACCTGGACTTATTCGTTCCGCAGGAGTTGATTGTT
TCCTCAGAGGGTCAGCATCATTCAATGAAGGACTGCTTTCAGGTTGTCCAGAGCTATCGG
TGAGATAGACACAGCTGTCCACATCTCCCAGTCGTACACATGTTCCACATGGTTTCGTTC
GATCGCACTTACTTTTCCTTTTTTTGCAATTTGTGCATACTACAGTAATTCGATGTCGTT
TTTTTGTCCTAACTTGGGAGTCATATCCCATTATGAGATCAGTTGTCAACTAAAGTCTGG
TATCAATTGGTTTCTAGTTTCTTTCTTCTCTTCATAGACTCATAACACTGCAAAATCGCA
ACAATAAATTCATGACTTATTGTTATGCAAAAAATTACCCGAATGTGAAAGATTAATAAG
CTCATCGCAGTCGCAGAAAGAGTGAAAAAAATACCTAAGAATGCCTAAATTAGCTTAAAC
AAAAGTCATTTCTAGAAAGCAATGAAAAAAGGGCAATCTA
Chr coordinates Chr XI from 562297-560789
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