Locus Information
Locus Info
Protein Info
GO Info
Orthologs
Standard Name
LAS1
Systematic Name
YKR063C
Strain
S288c
Description
Endonuclease involved in pre-rRNA processing at both ends of ITS2; functions with Grc3p in a conserved mechanism to cleave pre-rRNA at a specific site during rRNA processing and ribosome biogenesis; may coordinate the action of the Rat1p-Rai1p exoRNAse; required for the G1/S cell cycle transition; human ortholog is Las1L; mutants require the SSD1-v allele for viability
External sources
Open in SGD
Open in KEGG
Gene Sequence
Download FASTA
Hide Seq
>LAS1 YKR063C
ATGATACCACCACGAATCGTTCCATGGAGGGATTTTGCTGAACTAGAGGAGCTGAAACTT
TGGTTTTACCCGAAAAGCAAAGGAACCATTGAAGATAAGCGACAGCGTGCAGTGCAAAGA
GTACAGAGCTACCGACTAAAGGGTTCCCAATATTTACCTCACGTGGTGGACTCTACAGCA
CAAATAACATGTGCGGTATTGCTAGACGAAAAGGAAGCGTGTTTAGGAGTACATCAGGAT
TCTATTCCTATCCGGTTATCGTATGTAATGGCTTTGATTCGGTTTGTCAATGGCTTATTG
GATCCAACGCAACAATCTCAGTTCGCTATTCCCTTACACACATTAGCTGCTAAAATTGGA
CTGCCGTCCTGGTTTGTTGATTTGAGACACTGGGGTACACATGAGAGAGATTTACCTGGA
TTAGAAATGCTTCGTTGGGCCGCCAATGAAGCGTTATCTTGGCTATATGATCACTACTGG
AACGATGAGGAATTAGAAGATGACAGGGATGATGATGACGATGATGATGATACCGGTTAC
GGATACAGAAGAAATGATAAACTGGAGAAATATATGGAGTCATTAACTAAAACACTTGAT
AAATGGAAGCGACTTAGAAACGAGTTTCTGGAATACAAATGGGTGTGGGAGAATGCAAAC
GATAGTTTAATTACAAGTAGTAACTTTTCTGGGGATAATTTGGTGAACTATGATGCCGAA
AAGAGGAAAAGTTCACACGCAAGTTCATCAGAAACTATGATCAGGGAAAATTTGCGTCAA
TGGCAAGAACTTTGGAAATTATCCATTTATCACAATGTGGTTCTTGAGAAATTTTTTAAC
AATTATGACCCACTTTTACTCAAAGTTTTAATGCTTAATTTGAACAATTTTGATTGGAAG
GTCATTGAGTGGGTAGCTAGGAATTACAGAACCCAACAAGATGATAGTAATATAACGACA
ATTTTAAAAAGGAAATTCAATGCCTGGAAAGAACTACAAAAAAGGCTGTTAGATGTTATT
ATAAATAACCTTAACAATAAAAATTTTAAAAATAAATGGCAAAATTGGGAGAAACTTATT
GATGAAAATGCGTCATACTTGATATTGTATTTTTGCCAATCTATGCTGGCCAAACTAGAG
ACTGAAAAAATTACTGGTAACTCATGGAGAAACAAAAAACGGAGAAAACAAATTGATAGC
ACAGTGGAAATCGAGGCAAAACTGAAGGAAAACATAGACAATTTATCATTAAGGTTTAAT
GAAGGTGAAATAAAGCTGTATGATTTTATTCCTGCGGAAAAAGATTCCGTTCCATTGAAG
AAGGAAGTGAGTCCGGCATTAAAGGCTGATACCAATGATATACTAGGCGATTTGGCGTCT
TTGAAACAGAGAATGAGCAGTTTCGGAACAGTAGGTAAAAAAAATAAACAAGAGGAGAAC
AGAGCTACACCAGTAAAAAATTGGTCAAGGGTTCAAAATTGGAAACCCAAACCCTTTGGT
GTCCTGTAA
Promoter Sequence
Download FASTA
>LAS1 YKR063C
CCTTTGCTAATATAGTTTCTGAGCTGAATTTTTTAGCATTATTTTCTCTGTATTGAGCGA
ATTTGTTAAACAATGATTTGTGAATAGTCTGATGCATGCGGAAGTTATTGCCCTTACCAA
CAACATCATCGCTAATGTGGCGTTCGTCATCAGCATCGAAAGTGGATAAAGCTTCGAAAG
ATTTAGGCAAGCTTCCATTTTTCACATTATTGCCGTTGCTTCCCAATTTATCCATCATTT
TTTTGATTGCGATACTTCTAAATGTTACCATTGCTTGGAGATAGGGGTCGCGATTTTCAA
TTGCTCTATCCGTGAACAGACCAAATAAATTATCAGCAGACCTTTTGGTCTCTAAATAAA
ACCCATTAGGGATGAGGTCAATAAAAAATGGAGTTTCTTCATGAATTGGTAGATAATAAA
GTGATGATTGATTTTCAAGTTCTCGTACTCTTTGCCAGTGATCTTCGTCTTGTCTTGTCT
GTGACGATCTTCTTTTCTTAATGAAACCTGGACTTATTCGTTCCGCAGGAGTTGATTGTT
TCCTCAGAGGGTCAGCATCATTCAATGAAGGACTGCTTTCAGGTTGTCCAGAGCTATCGG
TGAGATAGACACAGCTGTCCACATCTCCCAGTCGTACACATGTTCCACATGGTTTCGTTC
GATCGCACTTACTTTTCCTTTTTTTGCAATTTGTGCATACTACAGTAATTCGATGTCGTT
TTTTTGTCCTAACTTGGGAGTCATATCCCATTATGAGATCAGTTGTCAACTAAAGTCTGG
TATCAATTGGTTTCTAGTTTCTTTCTTCTCTTCATAGACTCATAACACTGCAAAATCGCA
ACAATAAATTCATGACTTATTGTTATGCAAAAAATTACCCGAATGTGAAAGATTAATAAG
CTCATCGCAGTCGCAGAAAGAGTGAAAAAAATACCTAAGAATGCCTAAATTAGCTTAAAC
AAAAGTCATTTCTAGAAAGCAATGAAAAAAGGGCAATCTA
Chr coordinates
Chr XI from 562297-560789