Yeastract
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YEASTRACT+ INESC-ID IST IBB
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Locus Information

Standard Name PRP16
Systematic Name YKR086W
Alias PRP23, RNA16
Strain S288c
Description DEAH-box RNA helicase involved in second catalytic step of splicing and in exon ligation; exhibits ATP-dependent RNA unwinding activity; mediates the release of Yju2p and Cwc25p in the second step; in the absence of ATP, stabilizes the binding of Cwc25p to the spliceosome in the first catalytic step; missense mutation in human ortholog DHX38 associated with early-onset retinitis pigmentosa
External sources Open in SGD external link
Open in KEGG external link
Gene Sequence
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Promoter Sequence
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>PRP16 YKR086W
CGTCTGCTCCATCGCTGTAGTCACTGTAAGCCATCTCGATAGTCAATAGTTGTCGAAGCA
GAAGCCTTTGGGTGTCTCCAAGCTGTACTTAACTCTTTTTAAATTGCTTATTGGTTAGCT
TTCATGTGGTATATTCAAGTCACATTAATGGGCGTCTCCGTGCATTGTGATCAATATATG
AATACGAAGTACTTATAGAGTAGTATTTACACGATTGTTATTATATTTATATAGCATTCA
CGCCTGGTACCACAGGAGTTTTCTACGCTTACGGTCCTCTCTGGCTATACGCCTCTTCTC
CTTCCAGCGTGATTGGATTTCTTGCAATCTACTTTCCATAATTTGTACATGTTGTTCACT
AGGTTTCGAGACCATGGATACAAATAATGGCGAAATGCCATATTTTGCAGCCAAAAATTT
GCGTGTATACTTTTGAGGATTGTCAAGACGTAACTTCCGGATCTCATCAATTTCTTGAGG
TCCCAGATGATAGGTTTTGCCGTTCACTGTGCTCTTACCTACGAGAACATTTGGACACTG
CTTCGCTTTAGTGCTTTGAACAGGCATGTCAAGCCCTCTACGAGGGTCACTGGCTGCCAT
AAAGCTACGTGGAATGGTCTCACTGTTAACAGATCCGGTTGCGATGGATTCTGATGGTTG
ATAGTACATTCCTGGAGCATCTCTGTGCTTTAAATACCCTTTATAGTTAGATGCGCTCTT
AGTCTTGTTGTAAATCGTTGTCACTTGTGTTTTGGGAAATCCAAATTGCTTCCAGGCAGA
TCCAGCAGTGTGGAACGATCTGCAGCACACACCTCTGCCAATCATTCTTGTGCTATTTTA
CTTTGTCTTTAATTTTCCATTTTAACTTGTTGAAAGTATCTCTTTTTGCCCTCTTTTCTA
TTTTCTCAAATAATAAAAGCGGTGAAAGCTGAAAAATTCATGAGATGACTGCAGATGATA
AAACACAAGAAGGCCCAAAGACAATACAAATACCTCTGGT
Chr coordinates Chr XI from 599857-603072
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