Yeastract
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YEASTRACT+ INESC-ID IST IBB
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Locus Information

Standard Name RTT109
Systematic Name YLL002W
Alias KAT11, KIM2, REM50
Strain S288c
Description Histone acetyltransferase; critical for cell survival in presence of DNA damage during S phase, required for recovery after DSB repair; acetylates H3K56, H3K9; H3K56 acetylation activity required for expression homeostasis, buffering of mRNA synthesis rate against changes in gene dosage during S phase; involved in non-homologous end joining and regulation of Ty1 transposition; prevents hyper-amplification of rDNA; interacts physically with Vps75p
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Gene Sequence
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Promoter Sequence
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>RTT109 YLL002W
ATTTAGAGAAAGACTTTTAGAGATAGTAAAATCAGAAGAATTAGCAGACGAAGTTCGCGA
AGAATTTGTGTTAGTCAAGACGTTTTATATTTGGAAAACTCATCTAGACGAAATATTTTA
TATGAGTACATTATTGGAACAATCGGAAGCTAATAAACAATTCATAATTACATCCAAATT
CTTGAAAATGTGGAGTCTTCGATTCCTAAAAATTAAGCGTAATGATGAGACAGTCGAGGT
GTTTCGTCATCGGTGGGACAGGGCCACTGTAAGGGGATTGTTATTATTATGGAAAAATCG
TTCAGACAGTTCTCCAAAGAGAAGGAAGGACTTCAATCTTAAACATGAACTAAAAACTCC
CATAAGATCAGACTCTCAAAACGCCTCAACCATACCAGGCTCAGAAAGAATAAAGCAGCA
CAGAATGGAAGCGATGAAGTCGCATTATAGCAGGGCAAGAAGAGCCATACCAAGTCCGGT
GAAATCTTCCAGTGTTCTTGATTCTACAGCTAAAAAACAGATCAACCTTGAAAGTACGAC
AGGCTTAAACGGATCTCCGACGCGAGGAAAACCTCTAAGGTATTCTCCTAGGCGTACCAC
TAGAAACATGCCATCCAAAGTTGACCATATTGATTTTGGCAGAATACCCGCTGTACCTTT
TAGCCTAAGCGCCAATTCTCCTAAAATCGATCAAGATATGGATTATATAAGAGAGCATGA
TAAATCCCCGTTAAGTCGTAAACGTCAATAGATATATATATTATGTACGTATGTATGTGT
GCATATGTAGTCGTAACCTTTCTTGCTTCTGAGATGCATACAATTACTAATAATATTCTC
CAGGTCTATGAAAACATCACAACATACTATACTTTTCGTGTTCGCGTTGTAAGCTATAAT
GGAAAATGGACGCCATAACGCATTACTTAACAAACTACAGTTTGTCAATAGAGTTGTCCA
GTAGAGTTAAAAGGTCAATTCAACCGGTCTTCAATAAGAC
Chr coordinates Chr XII from 146291-147601
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