Locus Information
Locus Info
Protein Info
GO Info
Orthologs
Standard Name
SIC1 Systematic Name
YLR079W Alias
BYC1, SDB25 Strain
S288c Description
Cyclin-dependent kinase inhibitor (CKI); inhibitor of Cdc28-Clb kinase complexes that controls G1/S phase transition, preventing premature S phase and ensuring genomic integrity; phosphorylated by Clb5/6-Cdk1 and Cln1/2-Cdk1 kinase which regulate timing of Sic1p degradation; phosphorylation targets Sic1p for SCF(CDC4)-dependent turnover; functional homolog of mammalian Kip1 External sources
Open in SGD
Open in KEGG
Gene Sequence
Download FASTA View Seq
Sequence hidden Promoter Sequence
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>SIC1 YLR079W
CCGTTTATTGATAGAGGTGATAGTTTGTTCCGAAACACCCAATGTTCTTAGGCCATTTGA
CATTCTATCTTGTACCTTGGATAAAATTTTGTTTTGTTCCACTATATTTTCGAATGATTG
TTGGCCCATTTCTAGAATGTAATCTAATTGAGCGTTACCCCTTTCGAAAACAGACTGTTC
CTTTTGTAGCCCTTGGTACAACGGTAGTCCCCCACCGTTGCTAGAGCCCTCTTTACCATT
TGCACTCGCACCACCAACGTTCCTTTTATTCATGATGGTCTCTGATGTACTAAAGGGGTT
ATCGGAGTCCATAACATGCGATGCTCCTGAGCCAAACAACTGAGTTCTGGAATTATTTTC
GTTGTAGGATTGTTTTAAATCCTTAAACTTGGCAGTAAAGTCGTGCAGATCCTGTGTTAA
AGTTGCTAGTCGATTAGCGAACTTAGGATCAATTTCCTCTGCATTAGTATCTTCTTTATA
TCTGTTTAAATGTTCTGCATATTGCTTAACTGTTTTCTCCAGTGAGACCAGAGTTGCAGA
GATGGACCCTTGTAAAGAAATAGGGGCGGTCACAGAATTCTTTTCAAACCTGGCCAACTC
TTGTTGTAGTTGATTTTTTTGCTTCACAGCATGGTTGTAAAGAGCGTTCTATTTGATGGT
AGTAGCAAAATACCCTGTTAGTATTACATCTTGTTTTAGCAATAATGAGAAAAGATGCCT
CCGGCGATCAAACATACCATTCCCCCCTCAAATCAATATGATTAAGTCACGATAATATCT
GCACTATTGCCGTGTTTCCTTCTCCATCGACAGCGTCGATCCTGTCTATTATAGCCAGCA
CACTGAAAATTTCAATGGCTGGCTTGTTGTTCGCGTCGCAACTTTTGATATTTATAAAAA
GAGAGAAGGCATATCCAAAGGATAAGGTATTGTCTTTGTAAATCAATCAACCAAACCTCT
ACGGAATTTTGACCCTTGAAGCAGGGACTATTACACGAAA
Chr coordinates
Chr XII from 286820-287674
