Locus Information
Locus Info
Protein Info
GO Info
Orthologs
Standard Name
CDC45 Systematic Name
YLR103C Alias
SLD4 Strain
S288c Description
DNA replication initiation factor; recruited to MCM pre-RC complexes at replication origins; promotes release of MCM from Mcm10p, recruits elongation machinery; binds tightly to ssDNA, which disrupts interaction with the MCM helicase and stalls it during replication stress; mutants in human homolog may cause velocardiofacial and DiGeorge syndromes External sources
Open in SGD
Open in KEGG
Gene Sequence
Download FASTA View Seq
Sequence hidden Promoter Sequence
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>CDC45 YLR103C
CCTAAACCCCTTGTTCTTTGCTTTGGGGCCCTTGACAGGGTCATCATATATTGCTCTAAA
CTTTTCATTGTGTGTGGCTGGTTTGGATATGCAAACAAATTTATTATCAGGAAGGACACA
TTTCAACTGAGATTTAGGGAAGGGACAAGGACAGTCTTTCTGCTGTGCAACGCACGTTAG
GGTGTCCGGACACAAATACCCATCACAAGGGTTATTTAAAACTTGATCTTCATATGATTG
TTGCTGTTGCTGTTGCTGTTGCTGATGATGACCGAAATTGAAGAAGGCATTCACTCCAGT
GCTGCCAAAAATAAACAATGCAAAGATGAGAACGATACTCCAGCGACTTTGACTCATACT
ACAGTAAAATTTGGTCGTTTTTTGCCTGGCAAACCATGCCTATTTTTCGTCATTAAAGGT
CTTCTGAGCTTTCATCAAAATTATCTCTATAATTATAAAGGACAGCTCAGAGCCACACCC
AAACATCTGCAAAGGTAAAGGCCATCTTTCATCTCACATTGCCTAACAAGAAAGTCACAT
TGCAATTGTTTCGAGAAGAAAACATTAATTCAATTACGTGGTTCCCATGCGTCTGTGTTA
AGCGTCAATTTATCATTTGACGAACTCGTTGCAACCACAAACAAAGCAAGGGCCGCATTT
ATCAAAGGAAAACCAACCAAAAGCATAAATAAACGAGATTTTTATTATGAAAAAGCCATG
CGAATCCTACTAGAATAAATTCAAAGTGAAGACATTTAGTCAATTCGATCTTCTCTCTCT
TGCTTTAACTAGTCGTAAAACCTAATAAGTTTCATTCACGACGCGTATTTTTTTTTCAAC
ATATCATCTAACGCGTTTTAAGAAATTTCAGTAAATAATGAAGCTGTAGTAATGCCAACA
ATCCATTGTGGCTACTTTATACAACGCACTATAGAGCAATAAAAGTGTAGCAATAAACAC
TAGAGAGAAGGCACATAATAACAAGAATATACTCTCGCAC
Chr coordinates
Chr XII from 345941-343989
