Locus Information
Locus Info
Protein Info
GO Info
Orthologs
Standard Name
ORM2
Systematic Name
YLR350W
Strain
S288c
Description
Protein that mediates sphingolipid homeostasis; evolutionarily conserved, required for resistance to agents that induce unfolded protein response; Orm1p and Orm2p together control membrane biogenesis by coordinating lipid homeostasis with protein quality control; protein abundance increases in response to DNA replication stress; ORM2 has a paralog, ORM1, that arose from the whole genome duplication
External sources
Open in SGD
Open in KEGG
Gene Sequence
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>ORM2 YLR350W
ATGATTGACCGCACTAAAAACGAATCTCCAGCTTTTGAAGAGTCTCCGCTTACCCCCAAT
GTGTCTAACCTGAAACCATTCCCTTCTCAAAGCAACAAAATATCCACTCCAGTGACCGAC
CATAGGAGAAGACGGTCATCCAGCGTAATATCACATGTGGAACAGGAAACCTTCGAAGAC
GAAAATGACCAGCAGATGCTTCCCAACATGAACGCTACGTGGGTCGACCAGCGAGGCGCG
TGGTTGATTCATATCGTCGTAATAGTACTCTTGAGGCTCTTCTACTCCTTGTTCGGGTCG
ACGCCCAAATGGACGTGGACTTTAACAAACATGACCTACATCATCGGATTCTATATCATG
TTCCACCTTGTCAAAGGTACGCCCTTCGACTTTAACGGTGGTGCGTACGACAACCTGACC
ATGTGGGAGCAGATTAACGATGAGACTTTGTACACACCCACTAGAAAATTTCTGCTGATT
GTACCCATTGTGTTGTTCCTGATTAGCAACCAGTACTACCGCAACGACATGACACTATTC
CTCTCCAACCTCGCCGTGACGGTGCTTATTGGTGTCGTTCCTAAGCTGGGAATTACGCAT
AGACTAAGAATATCCATCCCTGGTATTACGGGCCGTGCTCAAATTAGTTAG
Promoter Sequence
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>ORM2 YLR350W
CTTGGGCATAGGAGCCGCCTGCAGTCTGACTTTGGCCAAGTCAAGAGGATGTGTCACCAT
GGTAGCAAAGATACCCGCTGCACCTCCGTACCACCATGGATACTTGATATTCTTACCGGC
AGACTCTTTTGCGTTGGTTGACATGCCGTCCAGCTGTTGCGTTATCTTTTCGACACTTTC
AGAGCAAGAGAAACGAACCTCTACACATAAATATGCATACGATTATGTATATCCATATAT
ATATATACACTACAAGCCGACCGCCCGACCGTTTCCTGCCCCCAACATTGCAGCGTAATC
GCTTGCCAAAGACCACACCTTGCAGCCCTTTTATACAAACATGTCTACGACGTACAGTGG
AGAGGGCCCTTTCCTTGGCACTCAACTGAGATTGCGACGCGATACCTTCTGCGACCGTTC
CTACTATCGCGGCCATAACTCCAACAACGACAGCGGATGCGCTGTTCTGCGGATGCGTGA
CCGTATCCGCAAAGAACGAAGATTAAATTTAGGGTCCCCGGCATTGAGGATGGTTCTGCC
AAGAACTCACGATATAAACCAGTTGGTTGAGCATCGCATGGATGAGTATGGCGTATTTTG
ATTGCTCATATATAGTGGGGGGGAATACTCATGCTGTGAAAAGCACAACTCTTTTCACTC
AACGAGGTTAATGCCTTCTTTGTCTCCACGCCGTTTTTTTCTGGCGCCCTTTTGAGAAAG
ATAGCCTGTCCCGTAATCGTGGCTTTGGCAGAGACAGAGGGTGAGCGAAAGAGCGGGCGA
AACCGAGAATGGATTCCGAGTAAAGGATTGCGATGGCATGAAACAAAACCGAGAGGCACT
CCTTGTAAGGACACACATACACAGACGTAAACATATATATACATACGTATACTCAAATAT
ATCTTCGTATCATTAGGTCAGCTTCTCTCTTCCGCACGTAGAATTAGAGAATTAACGCAA
GACTATACCATTATAAAAACGCATAAGAAACAGTTTCATC
Chr coordinates
Chr XII from 828730-829380