Locus Information
Locus Info
Protein Info
GO Info
Orthologs
Standard Name
CDC73 Systematic Name
YLR418C Strain
S288c Description
Component of the Paf1p complex; binds to and modulates the activity of RNA polymerases I and II; required for expression of certain genes, modification of some histones, and telomere maintenance; involved in transcription elongation as demonstrated by the G-less-based run-on (GLRO) assay; protein abundance increases in response to DNA replication stress; human homolog, parafibromin, is a tumour suppressor linked to breast, renal and gastric cancers External sources
Open in SGD
Open in KEGG
Gene Sequence
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>CDC73 YLR418C
ATGGCGAACTCATTAGACAGACTGAGAGAACACTTAAAGAACGGCGATAAACTGGTTCTA
AAAAATAATGAGGGACAGTCTACTGATGATATTACGAAAGCAACCATGGTAGAAACTCTA
TCCAGTGATGGTAGTACCCAAGATAGTTTTCCATTGAATGAAGAAACGGAAATTGAGATT
GATGGTTCATTGGTACAGTTACGAATAATTGTTCATTGTTGGATGAATAAGGACTCAAGT
GCCGCAGACTATCTAGCAGACTGTCAGAATAAACAATTGACTAATGTTTCATTTTTACAA
AGAACTGATTTAATAAATTGGTTGTCTGGCAATACGGAATCATCCCAATATCTGAAAGCA
CCCGGTCAGAAAGGCGAGACATCCGATAAAGTAGATATAGAAAATAAAACTTTGGCTGGT
GAATTGTCGACTGTAAAATCAACCACTTCAGCATCTCTTGAAAATGATAGTGAAGTTTCC
GATCCAGTTGTGGTGGAAACAATGAAACATGAACGTATATTGGTGGACCACAACTCTGCA
TTGCGTGGTGCTAAGCCGATCAACTTTGGTTATCTAATAAAAGATGCAGAACTAAAATTA
GTACAGTCGATCAAAGGATCTTTACGAGGATCTAAATTGCCTCCCGGTCATAAGGGCGCG
CACGGTCGTATTTCCAAAACAAATGGTTCATCAGGTGGCCCTCGCAAAGATCCAATTATT
TTGATTCCTTCGGCTGCGTCATCAATTTTAACTGTTGCAAATATAAAACAGTTCCTGCTG
GAGTCAAAATACGTGAATCCTCGTAACTTACCGTCAGTGCCAAACGGATTAGTTAACATA
GAGAAAAACTTCGAACGTATATCAAGACCAATTAGATTTATTATAGTCGATAACACTAGG
ATGTTTACTAAGCCAGAATATTGGGACAGAGTTGTCGCTATCTTCACTACTGGTCATACG
TGGCAGTTTAATAACTATCAGTGGAATTCGCCACAGGAATTATTTCAACGCTGCAAAGGC
TACTATTTCCACTTTGCCGGTGATTCTGTACCACAACACGTGCAGCAATGGAATGTAGAA
AAGGTCGAACTTGACAAAAATAAAAGATTTAAGGATGTGGAAGTCGTGCGTTATTTCTGG
CATAGTTTAGAAAAGGAACTTATTTCAAGAGGATACCGTTGA Promoter Sequence
Download FASTA
>CDC73 YLR418C
CGTGCAACTTGTTCTTTCTGTGCTTGATTATTCTGGGCCACTTGTTCTTTTTCACGTTGG
GCTTTGAGCTTTCTGTCTTCCACCATTGTCTTGAAGGGATCAAGATCAAATAGTTTGTTT
ATACGCTTTTCGTCTGTTTTCAGGTTATCTTTTCGAAAATCGTCGAGGGCATACCATGTT
TTTCTATGGTTTGGCGGAAGCATCATGTGCAGGTTGGTGTTGTATGCAATGCGATATAGC
GCAATAGTGGAGGCCATGTGTCTAGCTTCAATTGGAGTTTCTTGAGGAATTACAAGGCCT
TTTCCTGAAGCTTTGTCATAGGTTGGATCGTTCATTCTTGCAGTCAATGTTTCTTTTGTC
TTTGGGTCAGTGAATGACAAAACTGCAATTGCAATGAAACCTTTATCACCGATTTTCTTC
ATATCATACTCTACCTTATTCCATTTTCGTTTCTGACATGTTTCGTGTAAGATTGTATGA
GGCAATTTACCTGTCCAGCTTGCTGTGGATGTCACTTTTGCTCTATTACTTTGTTGCTTG
GCCCTTTTGTCATCTTCTGGCTCTGGTTCTTGTCCCTTTTTTCCTTTTGCTTTCTTTTTG
CCAGCAGTTGTTGGTACATCATTCACTGGAGTTGAACTTTTTGAGTTATTTTTCGTTTTT
TTGGCCATTTATCAAAAATTAATGAAAGCAATTGCGATGTAAAGTATAAAGTGAATGATT
ATTGTTAATACTTCCCTTAGCTAAGAGTCTCTTTTACAACTTTGAATAGTATGTATCTTT
TTAGTGTATAATTTTTCAACTCATCGAACACCGAGACGGTTAACCGGCAACGCAATATTG
TTCTCAAAGCATAAGGATGAAAATTTCGATTGGACAGGTTTAAAACAAGTACTTCAACGA
ATATTCCACCCTTTTTCAAATTGCGTTTCCAAAACAGGCTGTTTCTTAATTCGGGGCGTT
AAAAGAATAATAATTTGAGCAAGAAACTGGTGAAAAAATT
Chr coordinates
Chr XII from 958095-956914
