Yeastract
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YEASTRACT+ INESC-ID IST IBB
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Locus Information

Standard Name LEU3
Systematic Name YLR451W
Strain S288c
Description Zinc-knuckle transcription factor, repressor and activator; regulates genes involved in branched chain amino acid biosynthesis and ammonia assimilation; acts as a repressor in leucine-replete conditions and as an activator in the presence of alpha-isopropylmalate, an intermediate in leucine biosynthesis that accumulates during leucine starvation
External sources Open in SGD external link
Open in KEGG external link
Gene Sequence
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Promoter Sequence
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>LEU3 YLR451W
GTAGAAGAATATGGTTGGGAAGATATGGAAGTTGTCTCCGTATCTGGTAACTATTGTACT
GATAAGAAACCTGCCGCAATCAATTGGATTGAAGGTCGTGGTAAAAGTGTCGTAGCTGAA
GCTACTATTCCTGGTGATGTCGTAAAAAGTGTTTTAAAGAGCGATGTTTCCGCTTTAGTT
GAATTAAATATATCCAAGAACTTGGTTGGATCCGCAATGGCTGGATCTGTTGGTGGTTTC
AACGCGCACGCAGCTAATTTGGTCACTGCACTTTTCTTGGCATTAGGCCAAGATCCTGCG
CAGAACGTCGAAAGTTCCAACTGTATAACTTTGATGAAGGAAGTTGATGGTGATTTAAGG
ATCTCTGTTTCCATGCCATCTATTGAAGTTGGTACGATTGGCGGGGGTACTGTTCTGGAG
CCTCAGGGCGCCATGCTTGATCTTCTCGGCGTTCGTGGTCCTCACCCCACTGAACCTGGA
GCAAATGCTAGGCAATTAGCTAGAATAATCGCGTGTGCTGTCTTGGCTGGTGAACTGTCT
CTGTGCTCCGCACTTGCTGCCGGTCACCTGGTACAAAGCCATATGACTCACAACCGTAAA
ACAAACAAAGCCAATGAACTGCCACAACCAAGTAACAAAGGGCCCCCCTGTAAAACCTCA
GCATTATTATAACTCTTGTAGTTTACATGGTGATACTTTATATCTTTGTATTGTCTAGCT
ATTCTAAATCATCTGCATGTAATAAGAAGTTGATCAAAATGACTCGCTGCGTAAAACCTC
TCTTCGATCGGAGGTGCCGCCTAATTTATCGCCTAGCACTGCGCTTTTTCAAAGTTTTTC
AGAGCAAAAAATGAAAAGTAATGAGCACAACAATAGAAGAGTATCATGATATATAAGGTC
ATAAAACTAGGTTTCAGGGGCTATCGGCAATTTGAGGAACCTTCAACCTGCCTCAAGTAA
AAATCGCTTCGTAACATTAATACAAATTCTTTTTGCAATT
Chr coordinates Chr XII from 1036093-1038753
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