Yeastract
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YEASTRACT+ INESC-ID IST IBB
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Locus Information

Standard Name HMG1
Systematic Name YML075C
Strain S288c
Description HMG-CoA reductase; catalyzes conversion of HMG-CoA to mevalonate, which is a rate-limiting step in sterol biosynthesis; one of two isozymes; localizes to nuclear envelope; overproduction induces formation of karmellae; forms foci at nuclear periphery upon DNA replication stress; HMG1 has a paralog, HMG2, that arose from the whole genome duplication; human homolog HMGCR can complement yeast hmg1 mutant
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Open in KEGG external link
Gene Sequence
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Promoter Sequence
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>HMG1 YML075C
CGGCAAAAAAAGCGTTATCTTCTTTCTGTTCCTATTTCACTGAGTGCTACTGGATGGTCG
TCAAGAAAGGTGAAGAAATCTTCAAAGCAATAAGAATTCAGACATTGACGTTAAATTAGA
TTATCGCCGCAGCTGTAATTGCGGTTATGGCCTCTAGTATTTAGTTCGATGTTAATGAAA
TAAAGCGCAAGCTGACTGTGAACGATAACCGCCAGGAAGGCTAGACACAGCTCTTCAGCT
AAACAGTAGCCGGAACACATATACATTAGGGAACATTAGAAATAAGGCTCTCGTTGATCA
TCCTTGTAACTGAAAATTAGAACCGTTAAACGCTGCTGATTGATGGATTCCAGCCGTTCT
CTTCCAACCCCTTTTACCCCGATTGTTCGTCCACTATCATGACTTATTATCCACTAAAGT
GGCGTTGGCTGTACATTCGGGTGATGGTAGTATGGTGAGCACATGCTTTAAGTCCGAGAA
ACTAAGCTACAAAACGGAATTTCAAAGGGCCCCATTTTTATCGGGTGGACTAAGGGAAAG
AAAAGCCTTCTGGAGAAGAGTTGGAAGACCTCAGCGTAGTGCGAAGAAAACGTAGTGCGA
GTCTCTACGCCCGCTCGTTTAAAACTCTATAGAACGTCCGAAAGAAAGGTCCGTACTAGC
TATAGGATCTCTACTTTACCTATTATTATCGCTAGGTGATAGCTTATAAAACAATTCATC
GGTTTCTTCCTCATTTTTCCTGTATCTTTTCGGCTATGAAAAGCTGTTGTTCGATAAATC
CAGGCAAAGATTTTTGAAAGTTTAAAAGATCTAATTTTCAAAGGCATTCCTTTAAAAAAG
ACAACTTGAAAGAGCTATATTCGTCTTCGGTTTTTTGATTTTTATTAACTTATTTTTTTC
TTCTTTCTACCCAATTCTAGTCAGGAAAAGACTAAGGGCTGGAACATAGTGTATCATTGT
CTAATTGTTGATACAAAGTAGATAAATACATAAAACAAGC
Chr coordinates Chr XIII from 118898-115734
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