Yeastract
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YEASTRACT+ INESC-ID IST IBB
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Locus Information

Standard Name MDM1
Systematic Name YML104C
Strain S288c
Description PtdIns-3-P binding protein that tethers the ER to vacuoles at NVJs; anchored in the ER membrane at nucleus-vacuole junctions and binds phosphatidylinositol 3-phosphate (PtdIns-3-P) in the vacuolar membrane via its Phox homology (PX) domain; expressed predominantly in late G1 to early S phase of the cell cycle; mutation affects nuclear and mitochondrial transmission to daughter buds; similar to 4 human genes, one of which (SNX14) is associated with neurological disease
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Gene Sequence
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Promoter Sequence
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>MDM1 YML104C
TCATCCCTAAACGAAGTAGGAACTTTGAAAGTTATACTGAACCTATATTCAAGCGCGCAT
TTGATAAGGATTAACGATGAACCAATTCTTGGGCAAATTACTCTGACCTTTATCTCCGAA
TTGTGTTCTATTGAGCCAATTGCTGCAAAACTCATCAACAGTGGATTGTATAGCGTTCTA
TTGGAAAGTCCACTATCTGTTGCAATACAGCAAGGTGATATAAAACCTGAATTTTCGCCT
AGATTGCACAACATTTGGAGCAATGGTTTGTTATCCATTGTTCTACTACTATTAAGTCAG
TTCGGTATCAAGGTTTTACCTGAGACGTGCCTATTTGTTTCATATTTTGGAAAACAAATA
AAATCTACAATATATAACTGGGGTGACAACAAGTTAGCAGTGTCAAGTTCGTTGATAAAG
GAAACGAATCAATTGGTTTTATTGCAAAAAATGCTAAACTTGCTAAATTACCAAGAATTG
TTTATTCAGCCTAAAAACTCTGATGATCAACAAGAAGCTGTAGAATTGGTTATTGGTCTA
GATTCTGAACATGATAAAAAAAGGTTAAGCGCTGCATTAAGCAAGTTTCTAACACATCCA
AAATACTTGAATTCAAGAATAATACCTACAACTTTAGAAGAGCAACAGCAGTTGGAGGAT
GAATCAAGCAGATTGGAGTTCGTCAAGGGTATCAGCAGAGACATTAAAGCATTACAAGAT
TCACTATTTAAGGACGTTTAACTTATTTTGCAGGTTATGTAAAGCTACATAATATAATAA
TGAACAGTGCAAGTGCAAGGGTGGCCCTTTGTTGCTATACTGCGGACTGCGACTGTATGA
GCTTTTTCCATCCCAGTTCTATCCATTGTGTACTTTTTTTTTTCATCGCCTTACGAACTT
CAAAAATATGTAAACAATAAGATAAGTAAATTAACCGAAGACTCTCATGCTTTGAAAGCG
CCATAAGTGCGCGTGTTTGTGCCTTCTGATATGATATCGT
Chr coordinates Chr XIII from 62322-58939
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