Yeastract
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YEASTRACT+ INESC-ID IST IBB
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Locus Information

Standard Name HFD1
Systematic Name YMR110C
Strain S288c
Description Dehydrogenase involved in ubiquinone and sphingolipid metabolism; converts 4-hydroxybenzaldehyde into 4-hydroxybenzoate for ubiquinone anabolism, hexadecenal to hexadecenoic acid in sphingosine 1-phosphate catabolism; human homolog ALDH3A2, mutated in Sjogren-Larsson syndrome, can rescue yeast hfd1 mutant; human ALDH3A1, but not ALDH3A2, rescues pABA- respiratory growth phenotype of hfd1 null; data suggest that dual functions of Hfd1p have diverged in human ALDH3A1, ALDH3A2
External sources Open in SGD external link
Open in KEGG external link
Gene Sequence
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Promoter Sequence
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>HFD1 YMR110C
CAATGCTGATGACAGTAATAACCAACTCGATGGAACAGGAAACGAGAATGATATCAGAAA
CAGAAGAGGGTGCGTTGGAACGTCATATAAACTAAATCGTGCAATCCAGAACGTTACAGA
TGCGGCCCGTGAATACTTTGAAGGCTTACCGGGCCAACCGTCAGTTCTTTCCCTTGAGAG
GAGATATGGGTCCACTTGGAGGCGATCTGCCAAAGAAAGGACTTTGTTCACTAAAAGAAT
GACCATCATAAAAAGAATAATAGATATAAAAGATGATCCAAGCAAATATGGTTTGTCGCT
ACCTGAGAATAAAATAAGTAGAAACCAAGCCATCAAGGTTGTCGAAAATATAAGATTGGG
AAACAATACCTTCAAAGGACATCATTGCCGATTATCAATGTCCCAGTTATACGAATACTT
CTCCAAAAAAATGGACAAACTCGAAGACTATTCACTTACTCTAAAGAGAAGAGGGAAGCC
AAGAAGAATTTTCTTGTTAGAAGAGAGAGAAGCTAGATTATCATTACAGCAGCCACATAG
TATACCAAATTCCAGTACAGGCACACCAGAACATGATCAAGACACTTAGAGGAAATGGAA
CAACGAATTTCCAGCCAAAAATTCCGAGTAGTTCATGATGAAAGATTTTTACATGCATTT
TATATATAAATATATACCGTCCTATATGGATTTCATGCCAACAGGGTATATAATAGACAA
TTACCGGTGTACTGATATATCAACTATCGACTCCAAGCCTTTTATCTATCAGTCAATTTT
ACATCAAGATCCCACTTTTAGATAGGTTCGAAAATTCAATCTAATATTAGTGATTTAATT
AGATGGTGGATTGCTTACCCTTTTTTTTGTCGTTTTAGGAGGAGATTCTTCGGATTTTAG
GGATAAACGGATACTCCATATATAAAAAACAAAACTTCAGGCATATTGATTATCTAAAAG
GAATATTCTAAAACCATAGCCATAGTAATTTATCACCAAC
Chr coordinates Chr XIII from 491992-490394
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