Locus Information
Locus Info
Protein Info
GO Info
Orthologs
Standard Name
DOM34
Systematic Name
YNL001W
Strain
S288c
Description
Protein that facilitates ribosomal subunit dissociation; Dom34-Hbs1 complex and Rli1p have roles in dissociating inactive ribosomes to facilitate translation restart, particularly ribosomes stalled in 3' UTRs; required for RNA cleavage in no-go decay, but reports conflict on endonuclease activity; Pelota ortholog; protein abundance increases in response to DNA replication stress; DOM34 has a paralog, YCL001W-B, that arose from the whole genome duplication
External sources
Open in SGD
Open in KEGG
Gene Sequence
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>DOM34 YNL001W
ATGAAGGTTATTAGTCTGAAAAAGGATTCTTTTAACAAAGGAGGAGCAGTGATTACTCTT
TTACCGGAGGACAAGGAAGATCTGTTTACTGTTTATCAAATAGTAGACAAAGATGACGAG
TTGATATTCAAGAAAAAATTCACCTCTAAACTTGATGAAGCTGGTAAGAAAAAAAGTACA
GATTTGGTCAAGTTGAAGATTAAAGTAATATCCGAGGATTTTGATATGAAGGATGAATAT
TTGAAATATAAAGGTGTTACTGTTACAGATGAAAGTGGAGCTAGTAATGTTGACATACCT
GTCGGCAAATATTTGAGCTTTACCCTTGACTACGTGTATCCCTTTACTATCATAAAACAA
AACTTTAATAAATTCATGCAAAAGCTCTTAAATGAAGCCTGTAATATCGAGTATAAATCA
GACACCGCGGCGGTCGTTTTACAGGAAGGGATCGCCCATGTTTGTTTAGTGACATCCTCC
TCTACTATTTTAAAACAAAAAATTGAATATAGTATGCCAAAAAAGAAAAGGACTACTGAT
GTACTGAAGTTTGATGAAAAAACTGAGAAATTTTATAAAGCAATTTACAGTGCAATGAAG
AAAGATTTGAATTTTGATAAATTAAAGACTATTATTCTTTGCTCTCCAGGTTTCTACGCT
AAGATATTAATGGACAAAATTTTCCAGTATGCCGAAGAGGAACACAATAAGAAAATACTC
GATAACAAAGGAATGTTCTTTATAGCCCACTGCTCCACGGGCTACTTACAGGGCATTAAT
GAAGTTTTGAAAAATCCACTATATGCTTCAAAGCTGCAAGATACTAAATACTCCAAAGAA
ATCATGGTGATGGATGAATTTTTGTTGCATTTAAACAAGGATGATGATAAAGCTTGGTAT
GGTGAAAAAGAGGTAGTTAAAGCGGCTGAGTATGGCGCAATTAGTTATTTACTGTTAACA
GATAAAGTTTTGCATTCAGACAATATTGCACAAAGAGAGGAATATTTGAAACTGATGGAC
TCCGTAGAGAGCAATGGAGGAAAAGCATTGGTATTAAGTACTTTGCATTCTCTTGGAGAA
GAACTTGATCAATTGACGGGTATAGCCTGTATTCTAAAATACCCGCTCCCCGATCTTGAT
GAAGACGATGGTGAGGAGTAG
Promoter Sequence
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>DOM34 YNL001W
AAGAACTATTTCGTGAGGTTCAGCCTCATTCTCACCCTTATAGATTATTCTACCTCTCTT
TTGAATCAAGGAACGGATAGAAGATAAAGAAGGCTTGCCAATCACTACGTATGGCGCAAT
AACCTTGAGCAACGGATATACGTTTTTGGTCAATTTGACGAAAACACCAGTATTAGTTTC
AACTAATCTTAGCAAAGACAAAATCTTAAATGCTTTGTTTGGAATATTTACAGCAAGCGG
ACCTCTTACTCTGACAATGAAAAGTAAAGCAGGTTTGCCATCGTAAGTAGTCTTTTCTCT
GATTAAACCATCGTCTTCTTCTTCTTCAGTCTCCTCCAAGTCGACAGAGTTCTCTTCGGC
GCCATTAGCTTTTTCTGTTATTTTCAGAATAAAATCTTTCCCAGATGCAATATGCTGCGT
TTCATTCTTTGCCTTCTTATCTTCTAATATAGACACTCTTTTAATTCTTTCCTTTTCCCT
AGAGGTAGCCAAAGTCTTTGCAACTATACTTTCAGCTCTGACAAATTTGTTCTTATTACT
TCTCTTTTTTTTGATTTGTTCTTCCCTCTTTTTCTTAGCTAATTCTTGTCTTTCGATTCT
AGTTCTATCAGCATTTCTTCTTTTCCTCAAAAGAATTTCTGGATTAGAATTAAGAGTTTG
CGCTTTACTGTCTTGAGTTGAAGACATTGTGACTTGTATATCTTATTCTTTTTCCCTGTG
GCAGCCTCTTCTTTCTAGGAACTTAATAACGAAAGTACCAAACAACTTAGACTTTTCTCA
TCTCATCGCTTCCCAGCTTTTTTTAAGCAGAGCTGAAAAAAATTTTCTTTTTACCAAAAA
TCCGTACTGCGTGATGAAAGTGTACATACATTATTCAATATTCACCTAGTTTTGTATATT
AATGTAAAATGTAATTTAATGAAGATCCCAAAAAATTAAGCATTCGTTGCTGCATCGTTG
TCATTTTGTTCAATTATCGCATTCCTATCATAGCAAAAAT
Chr coordinates
Chr XIV from 627456-628616