Locus Information
Locus Info
Protein Info
GO Info
Orthologs
Standard Name
TCB2
Systematic Name
YNL087W
Alias
tricalbin
Strain
S288c
Description
ER protein involved in ER-plasma membrane tethering; one of 6 proteins (Ist2p, Scs2p, Scs22p, Tcb1p, Tcb2p, Tcb3p) that connect ER to plasma membrane (PM) and regulate PM phosphatidylinositol-4-phosphate (PI4P) levels by controlling access of Sac1p phosphatase to its substrate PI4P in the PM; contains 3 calcium and lipid binding domains; mRNA is targeted to bud; TCB2 has a paralog, TCB1, that arose from the whole genome duplication
External sources
Open in SGD
Open in KEGG
Gene Sequence
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Sequence hidden
Promoter Sequence
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>TCB2 YNL087W
AACCAAAAGCAAGGCGCCTACAAAGATTAAAAAAGAGAAAACGCCTTCTGTTTCAGAAAC
AAAAACAGAAGAAGAAGAGAATGCTCCTTCTTCCACGAGTTCTTCTTCTATTTTCGACAT
AAAGAAAGAAGATAAAGATGAGGGCGAACTGAGTAAGATTTCGAACAAGTTTAAAAAAAT
TAGCACGATTTTTGACAAAATGGGTTCTACTTCCGCTACATCGAAGGAAAATACACCAGA
ACAGGACGATGTAGCCACTAAAAAAAATCAAACAACCGCTAAAAAAACAGCTGTAAAACC
TAAATTGGCCAAGAAGCCAGTCAGGAAACAACAAAAAGTTGTGGAACTATCTGGTGAAAG
CGACCTAGAAATTTTAGATTCATACACTGATCGGGAAGATAGCAATAAAGATGAAGATGA
TGCTATACCACAACGATCAAGGAGACAAAGATCGTCGAGAGCTGCGTCGGTTCCTAAGAA
ATCTTACGTTGAAACTTTAGAATTATCTGACGACAGTTTCATCGAAGATGATGAAGAGGA
AAACCAAGGATCAGATGTTTCGTTCAATGAAGAGGATTGAATAATATTTATCCAGAGAAA
GCGCCATTCTTTTTATATGTTTATATCAGAAACAAATAGAAGTCGATCGTAATGACTAGA
TTATATAATCAGAAATAGCCTTTGGTGATCACTTCCATTTTAGTCAGCATAATAGAAAGT
TTAATTACGCGCTTTTTTACATTCCGACAAAGATCTGCCCGAGAAAATTCTTCGAGAAGA
CAACAACAACAAAAAAAATAAAGCCTGGGCGAAAAACATCGTGCGTTTACATAATATCTT
GAAAAGCAAACAGATATATAAACCGCTATTGAAATTACCTTTTTAAGTATTCGCCTAGAA
GCCTTGTTTCAAGTAGCATCAACAACAGGTGTTAGGTTAAACTGCTTTGACTTTTTGTTC
TTTAACGAATATCATTAAAAAAAAAGGACATCTATAAAGA
Chr coordinates
Chr XIV from 462411-465947