Yeastract
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YEASTRACT+ INESC-ID IST IBB
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Locus Information

Standard Name TCB2
Systematic Name YNL087W
Alias tricalbin
Strain S288c
Description ER protein involved in ER-plasma membrane tethering; one of 6 proteins (Ist2p, Scs2p, Scs22p, Tcb1p, Tcb2p, Tcb3p) that connect ER to plasma membrane (PM) and regulate PM phosphatidylinositol-4-phosphate (PI4P) levels by controlling access of Sac1p phosphatase to its substrate PI4P in the PM; contains 3 calcium and lipid binding domains; mRNA is targeted to bud; TCB2 has a paralog, TCB1, that arose from the whole genome duplication
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Gene Sequence
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Promoter Sequence
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>TCB2 YNL087W
AACCAAAAGCAAGGCGCCTACAAAGATTAAAAAAGAGAAAACGCCTTCTGTTTCAGAAAC
AAAAACAGAAGAAGAAGAGAATGCTCCTTCTTCCACGAGTTCTTCTTCTATTTTCGACAT
AAAGAAAGAAGATAAAGATGAGGGCGAACTGAGTAAGATTTCGAACAAGTTTAAAAAAAT
TAGCACGATTTTTGACAAAATGGGTTCTACTTCCGCTACATCGAAGGAAAATACACCAGA
ACAGGACGATGTAGCCACTAAAAAAAATCAAACAACCGCTAAAAAAACAGCTGTAAAACC
TAAATTGGCCAAGAAGCCAGTCAGGAAACAACAAAAAGTTGTGGAACTATCTGGTGAAAG
CGACCTAGAAATTTTAGATTCATACACTGATCGGGAAGATAGCAATAAAGATGAAGATGA
TGCTATACCACAACGATCAAGGAGACAAAGATCGTCGAGAGCTGCGTCGGTTCCTAAGAA
ATCTTACGTTGAAACTTTAGAATTATCTGACGACAGTTTCATCGAAGATGATGAAGAGGA
AAACCAAGGATCAGATGTTTCGTTCAATGAAGAGGATTGAATAATATTTATCCAGAGAAA
GCGCCATTCTTTTTATATGTTTATATCAGAAACAAATAGAAGTCGATCGTAATGACTAGA
TTATATAATCAGAAATAGCCTTTGGTGATCACTTCCATTTTAGTCAGCATAATAGAAAGT
TTAATTACGCGCTTTTTTACATTCCGACAAAGATCTGCCCGAGAAAATTCTTCGAGAAGA
CAACAACAACAAAAAAAATAAAGCCTGGGCGAAAAACATCGTGCGTTTACATAATATCTT
GAAAAGCAAACAGATATATAAACCGCTATTGAAATTACCTTTTTAAGTATTCGCCTAGAA
GCCTTGTTTCAAGTAGCATCAACAACAGGTGTTAGGTTAAACTGCTTTGACTTTTTGTTC
TTTAACGAATATCATTAAAAAAAAAGGACATCTATAAAGA
Chr coordinates Chr XIV from 462411-465947
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