Locus Information
Locus Info
Protein Info
GO Info
Orthologs
Metabolism
Standard Name
BIO4
Systematic Name
YNR057C
Strain
S288c
Description
Dethiobiotin synthetase; catalyzes the third step in the biotin biosynthesis pathway; BIO4 is in a cluster of 3 genes (BIO3, BIO4, and BIO5) that mediate biotin synthesis; BIO3 and BIO4 were acquired by horizontal gene transfer (HGT) from bacteria; expression appears to be repressed at low iron levels
External sources
Open in SGD
Open in KEGG
Gene Sequence
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>BIO4 YNR057C
ATGAACAGCAAATCTCAACAACAAGAACAACAACCAATTGTATTCGTCACCGGTACAGAC
ACTGATGTTGGTAAAACCTTTGTATCAACATTATTGGTACACAAATGGAAAGCTGCATAC
TGGAAACCCGTACAAACTGGAATTGAGTCAGATCAAGGTGACTCCGAGACATTGAAAAAT
TTCAAAATAGCCGCATCAACTTGGCAACCACCTATATTCACGCCCACTTATGCGCTGCAG
AAGCCTCTATCTCCGCTCCAGGCCATGGAGTACGAACCTAATGTCGACATCAGGTTGTTG
GATTTCGTAGTTCCTGAAGAGTGGAGCGCAGAGAATCCATTGGTCGTAGAAGGAGCCGGC
GGGGTTTGCGTTCCTATCACTCGTAAATTGGAAATTACGACGGATCTAATTAAACATCTG
ATTGAGACTAGCGGCCATCCAGTGTACGTAGTTGTCGTGGCACGCAGCGGGCTAGGGACT
CTGAATCATACATTGCTGACTTGGAATCATCTTTGCGATAATGGCTTGAGAAGCCACCTT
TTTGGGGTCATTCTCAATGGGGAACCGAATGAAGGCAACGTGCAGGCCCTGAAGAAGTTC
GGTGTCAATATTATGGCACAGGTTGCACAATGTACTACGGCACATGATCAGGATATGGAG
TTGCATGAACTGCCATCGGTGGAGTCATTAATGACCCAACAAGACGTAGAATAG
Promoter Sequence
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>BIO4 YNR057C
CATAGTTTCTGAACTTCGATTAAGAACTGTGGATGGTATGGTCGCAAACCTCCTGCACCC
TGTAAGATAGGCTCCAAAATCACAGCACAGATCTTATCACTATGCAATTCAAATTGCTTC
TTGAGATCGGTAACTTCTTCTGCATTCCAATGGTCCTCGAAACCGTTCTGGCTGGTTGGA
AGGCCATCGACAATAGAGGGAGCTTGGGCGAAGATGTTCTCACTGAGTCGATCGTTGTAG
ATATGATGCATAGAATTCTCAGGATCACAAACACTCATAGCGCCAAATGTATCACCATGA
TACCCGTTCTTGATTGTCAAAAACTTTGTTCTATTTTTAGTAGCTTCCCCTGACATGTTT
GATTGTAAAGCCATCTTCAAAGCTACTTCCACTGCTACTGAGCCAGAATCTGCGAGGAAA
CAGTACTGCAAAGAGGGTTCATCAATCACTTTTAAAAGTTTTTGGACTAGATTCACAGCT
CCTTTATGGGTGAATCCACCAAGAAGGACGTGAGAAAACTTTAACATCTGCTTGGTAAGG
GCCTCATTTAGTTCTGGATTATTGTACCCGTGAATAACACACCACCACGACGACATGGCG
TCGATCACCTCGACGTCCACTGGTGAGTCGGTATCCAACACCAGCTTGCATCCGTGAGCA
CTCTTTACCGGATAAACGTTCAATGGTGAACTCAATGACGTATAAGGATGCCAAATATGT
TTTTTATCAAAGTCTAGCAGTTCCGCGACATCTGGTGTATATGAAATTTCTTGGGACATT
AGTTGTTATCCTAGCAATAGAAAACGAATTGCGCTGTTGACATCCTCCCGACCAAAAGAA
AATGAAATATACAAACAATGGCTATTTATAATTCAAAATTATTGGGCAAAACAAAATAAA
ATCCCGCTGGTAGTTCGTTTACTGAAGTATATAAAGAGATATACTTTTTTCCACAAGTAG
GCCAGTGAAAAGAACTCAAAAAATCACTAGCGCACAGGTC
Chr coordinates
Chr XIV from 734069-733356