Locus Information
Locus Info
Protein Info
GO Info
Orthologs
Standard Name
CDC33
Systematic Name
YOL139C
Alias
eIF4E, TIF45
Strain
S288c
Description
Translation initiation factor eIF4E; mRNA cap binding protein and subunit of the mRNA cap-binding complex (eIF4F) along with eIF4A (Tif1p/Tif2p) and eIF4G (Tif4631p/Tif4632p), that mediates cap-dependent translation; required with eIF4G for Ded1p-mediated stimulation of mRNA recruitment during 48S preinitiation complex (PIC) assembly; protein abundance increases in response to DNA replication stress; human homolog EIF4E can complement the cdc33 null mutant
External sources
Open in SGD
Open in KEGG
Gene Sequence
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>CDC33 YOL139C
ATGTCCGTTGAAGAAGTTAGCAAGAAGTTTGAAGAAAACGTTTCAGTCGATGATACCACA
GCTACTCCAAAGACTGTTTTAAGTGACAGTGCTCACTTCGATGTCAAGCACCCATTGAAC
ACCAAATGGACTTTATGGTACACAAAGCCAGCCGTCGATAAATCTGAGTCGTGGTCTGAT
CTATTACGTCCCGTCACTTCATTCCAAACTGTTGAAGAATTTTGGGCTATCATTCAAAAT
ATTCCTGAGCCACACGAACTACCATTGAAATCAGATTACCACGTCTTCCGTAATGACGTT
AGACCTGAATGGGAAGATGAAGCCAATGCTAAAGGTGGTAAATGGTCTTTCCAACTTAGA
GGAAAAGGTGCTGATATTGATGAATTATGGCTAAGAACTTTACTAGCAGTTATTGGTGAA
ACAATTGATGAAGACGACTCCCAAATTAACGGTGTCGTTTTAAGCATTAGAAAAGGTGGT
AACAAGTTTGCCTTATGGACTAAATCTGAAGACAAAGAACCACTATTGAGAATTGGTGGT
AAATTCAAGCAAGTTTTAAAATTAACCGATGACGGGCATTTGGAATTCTTTCCACATTCC
AGTGCCAATGGTAGACACCCTCAACCATCAATCACCTTGTAA
Promoter Sequence
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>CDC33 YOL139C
TTTTAAAAAGCTTTCTTCCCATACAGCACCAATAATCGGATCGCCCAGACATGCGCCATC
ACGGCCAGATAGCATTGGTAGGGAACAACTGTCTTCTTCATTGACGAAAAAGCTTGCCAA
ATGCAAGAAAATTATCGCTGACCCACCCTGGGACACGAAAAAACTCATCAAACAACTCTA
CAATCAAGCTACTGAGACTGGGAACGTCGTATTGACGGTGAATATTTTATTTCTTTTCCA
AACGATATACCAAATAACAGAAATCGACATTGCAAAGGACGCAATCGCTCACTTCTTGTT
ATTATTACATCGATACGAACTCTTCGGCATTGCTGCAGACGTCTTAAAATACTGCCCATT
CGAAGATATCATGGGTTCTGAGGGTGACCAATCTTCCATTCGGTTGTTTTGCGAACGCTG
TGGTGAGTTAATCACTAACGAAAGTTCTAAAGAAAAGCTCAGAGCGGAAGCTCAGCAGAC
GGGCAATAAGAAGATCATGGACAAGTTTGGATACTGGTATTGTGACTCTTGTAAGAAGAA
GAATACATCTTGTGTTCTATGTGAAAGACCATTAAAGAAACTGACCATGGTCATCCTCCC
CTGTGGACACGAAGGTCACTTCCAGTGCATACAAGAATGGTTTCTCGATGAGAATGAACA
AGAATGTCCCGGCGGTTGCCCCGGTGTTGCATTCATCTAGGTTCTCCACATAATGTATAG
TTTAACATATCATCACCATTGTTTAGTTAAATCGTTTAGAGTAATATTACCCGTCAAAAA
GGTCGGGTAAAATTTTATTACCCTCTCCGAAAAGAAAATTTTTTTCGTCGTCAATAGAGT
TTAATGCAATACCTGATAAAGAGAGTTTTACATTGCAAGAGGTAGTGTTAATTCTGGATT
TATATTGTACATATGTGTTTGTGTTAGTGCTTGAGTACTTCCTAGGAGTTTTACGAAAAA
TAAAAGCATTTTTGTCTGAAAACTAGTGAAAGGAAGAAAA
Chr coordinates
Chr XV from 61024-60383