Yeastract
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YEASTRACT+ INESC-ID IST IBB
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Locus Information

Standard Name CDC33
Systematic Name YOL139C
Alias eIF4E, TIF45
Strain S288c
Description Translation initiation factor eIF4E; mRNA cap binding protein and subunit of the mRNA cap-binding complex (eIF4F) along with eIF4A (Tif1p/Tif2p) and eIF4G (Tif4631p/Tif4632p), that mediates cap-dependent translation; required with eIF4G for Ded1p-mediated stimulation of mRNA recruitment during 48S preinitiation complex (PIC) assembly; protein abundance increases in response to DNA replication stress; human homolog EIF4E can complement the cdc33 null mutant
External sources Open in SGD external link
Open in KEGG external link
Gene Sequence
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>CDC33 YOL139C
ATGTCCGTTGAAGAAGTTAGCAAGAAGTTTGAAGAAAACGTTTCAGTCGATGATACCACA
GCTACTCCAAAGACTGTTTTAAGTGACAGTGCTCACTTCGATGTCAAGCACCCATTGAAC
ACCAAATGGACTTTATGGTACACAAAGCCAGCCGTCGATAAATCTGAGTCGTGGTCTGAT
CTATTACGTCCCGTCACTTCATTCCAAACTGTTGAAGAATTTTGGGCTATCATTCAAAAT
ATTCCTGAGCCACACGAACTACCATTGAAATCAGATTACCACGTCTTCCGTAATGACGTT
AGACCTGAATGGGAAGATGAAGCCAATGCTAAAGGTGGTAAATGGTCTTTCCAACTTAGA
GGAAAAGGTGCTGATATTGATGAATTATGGCTAAGAACTTTACTAGCAGTTATTGGTGAA
ACAATTGATGAAGACGACTCCCAAATTAACGGTGTCGTTTTAAGCATTAGAAAAGGTGGT
AACAAGTTTGCCTTATGGACTAAATCTGAAGACAAAGAACCACTATTGAGAATTGGTGGT
AAATTCAAGCAAGTTTTAAAATTAACCGATGACGGGCATTTGGAATTCTTTCCACATTCC
AGTGCCAATGGTAGACACCCTCAACCATCAATCACCTTGTAA
Promoter Sequence
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>CDC33 YOL139C
TTTTAAAAAGCTTTCTTCCCATACAGCACCAATAATCGGATCGCCCAGACATGCGCCATC
ACGGCCAGATAGCATTGGTAGGGAACAACTGTCTTCTTCATTGACGAAAAAGCTTGCCAA
ATGCAAGAAAATTATCGCTGACCCACCCTGGGACACGAAAAAACTCATCAAACAACTCTA
CAATCAAGCTACTGAGACTGGGAACGTCGTATTGACGGTGAATATTTTATTTCTTTTCCA
AACGATATACCAAATAACAGAAATCGACATTGCAAAGGACGCAATCGCTCACTTCTTGTT
ATTATTACATCGATACGAACTCTTCGGCATTGCTGCAGACGTCTTAAAATACTGCCCATT
CGAAGATATCATGGGTTCTGAGGGTGACCAATCTTCCATTCGGTTGTTTTGCGAACGCTG
TGGTGAGTTAATCACTAACGAAAGTTCTAAAGAAAAGCTCAGAGCGGAAGCTCAGCAGAC
GGGCAATAAGAAGATCATGGACAAGTTTGGATACTGGTATTGTGACTCTTGTAAGAAGAA
GAATACATCTTGTGTTCTATGTGAAAGACCATTAAAGAAACTGACCATGGTCATCCTCCC
CTGTGGACACGAAGGTCACTTCCAGTGCATACAAGAATGGTTTCTCGATGAGAATGAACA
AGAATGTCCCGGCGGTTGCCCCGGTGTTGCATTCATCTAGGTTCTCCACATAATGTATAG
TTTAACATATCATCACCATTGTTTAGTTAAATCGTTTAGAGTAATATTACCCGTCAAAAA
GGTCGGGTAAAATTTTATTACCCTCTCCGAAAAGAAAATTTTTTTCGTCGTCAATAGAGT
TTAATGCAATACCTGATAAAGAGAGTTTTACATTGCAAGAGGTAGTGTTAATTCTGGATT
TATATTGTACATATGTGTTTGTGTTAGTGCTTGAGTACTTCCTAGGAGTTTTACGAAAAA
TAAAAGCATTTTTGTCTGAAAACTAGTGAAAGGAAGAAAA
Chr coordinates Chr XV from 61024-60383
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