Yeastract
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YEASTRACT+ INESC-ID IST IBB
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Locus Information

Standard Name ISU2
Systematic Name YOR226C
Alias NUA2
Strain S288c
Description Mitochondrial protein required for iron-sulfur protein synthesis; performs scaffolding function during Fe/S cluster assembly; involved in Fe-S cluster assembly for both mitochondrial and cytosolic proteins; protein abundance increases under DNA replication stress; ISU2 has a paralog, ISU1, that arose from the whole genome duplication; isu1 isu2 double mutant is inviable; human homolog ISCU implicated in mitochondrial myopathy, can complement isu1 isu2 double mutant
External sources Open in SGD external link
Open in KEGG external link
Gene Sequence
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Promoter Sequence
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>ISU2 YOR226C
ACCTTCTCGGCGGATACTGCTGGTTTAGAGTTGGATAATTCGTTATTTACATTCTGGCCG
CTCAGGGGCCTTTGAGGAGAAGCTATAGTTTTCGTAGGAACAGCTGCGGTTGATGGCAAA
GTAGCAGTTTTCTTTACAGAGGTGGTGGTAGCTTCTGAAGTGCGCGTGGAAGCCGCACTT
TTGGTCCTATTCCTTCGTTTCCCCTTATACAACCAGTCCAATGGCACATCTATATCAGTG
TACTTCAACTTGGAGCTCATGTCAGACTAGATTCAACCAGATACAAATTAATACATATAC
AATGGCCAAAGAGAATGAAGAAAAAAGGAAGGGACTCAGTCAAATATTAGACGACAGTAT
CACTGAAGGAAGGGAACTGGTGCGAGGAGGAAAGGAGAAAATACGTAATGCAAGTGGTAA
TAAAACGGGAACAGGCTAGTTCTCGAGAAATGTGGCAACTGCAACCAAATGGAAGAGTCA
AATGTAAGTTATAGAGGGTTCGCTTTCCACCTTAACCCATCGAACTGTCAATCATGTCGC
TTCTTTAACCTGCCCCTTAACGTTACTAAGCAAAAACAAAAGGCAGACAAACTCAAGAAA
TAATTAAGCATAACCCGGAAAAGGAAACGCCAAACCACTATGGAATTATTCTTATTTCAT
TACAGGGTCCGCACCTTCCCAGTCTAGAAAGGCATGGTATGGAATTATGACTGCAACTTT
ATAGTGGTCAGATGTTTATATATGTACACCCATAATACAGATACACAGCATACTGCATAT
ATCCGAGTCACCATGATTCTATTGTTTCAGAGTCCGGTTCAGGCCCAACGTTTTTTGGCG
CCCTCGTTTTTTCCCTATGCGGAACCTACTATTAATAAGCACCTGGGGCCGGCCGGTGCA
GCAGTATAGCAGTATATAACAACAGCAAAAGAAGCATATGTAGACAACGCTGAGGTTTCA
TTACAGCTCATACATCACCAACAAACATAGCACAGCATAG
Chr coordinates Chr XV from 762084-761614
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