Yeastract
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YEASTRACT+ INESC-ID IST IBB
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Locus Information

Standard Name PNG1
Systematic Name YPL096W
Strain S288c
Description Conserved peptide N-glycanase; deglycosylating enzyme that cleaves N-glycans that are attached to misfolded ERAD substrate glycoproteins prior to proteasome-dependent degradation; localizes to the cytoplasm and nucleus; activity is enhanced by interaction with Rad23p; human ortholog NGLY1 is associated with a syndrome characterized by developmental delays, epilepsy, absence of tears and liver disease
External sources Open in SGD external link
Open in KEGG external link
Gene Sequence
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Promoter Sequence
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>PNG1 YPL096W
CAGTTCTTTTATAATACTTTGGATGCTGATGTACCCAAGTTCTTGAAGATCTTTACGTTT
TTAAACTCAAGTGAAATCAAAAAAATTGTGGAAACGCATATCAAATCACCCAGTCTACGT
TATGGCCAAACTTTATTGGCTAAAGAAGTCACAGATATGTTATATGGAGTTGGCTCCGGA
TCGGATTCAGAAGCGCTTTCTAATATTATTTTTGGACGTTATGACGGAACTTTATCTGCT
GCGAAGTTAGTTGATCTATGTAAAAAAGCCAGAATTTTGCAGTATGCTGATAGAGAGATT
GACTTAATAAAGTTAATTTGTAAACTAGTAAATTGTTCAGTATCAGAAGCCAGAAGAAAA
CTTTCCCAGGGAAGCGTGTATCTGCATCATTCAAAATCTAAAGTAAACGAAAATATTTCT
AACTTGGCTCCTTTCCTGATAGATGATCGAGTACTGATCTTGAGGATAGGAAAGCAGAAG
TGTTTTATAATAGAAATGCGTTAAAAAAAAGGGAGGTATATAAAGTACATGTATAAAATA
GGCATGCGTGAGGTGATATTATATCATTTTATGCACTGACTTGTAAATAAGATTATAAAC
GATTATTCATCTTTACTACTTGCGAACATTTCACTGTCACACCAGGCTATGAGGGCCCAC
AGCCAGAGAGTCGCAGGGCATAGCAGTAATACACACCAGTAGTGCAGGAAAGAGTCATTG
TTGCGTAACCAGTAAAATGTAGCAAGACTAATTAGGAGTACCGAGTAAGTAAACCCTAAA
ACCAAAAAGCCTTGGTCACGTGGTCTCATGCGCTTATAAATTCTCAATCATGTAATTGAA
ACAGTCCTGTTGCCTAGTTTCAACTGTTCTATGCTTCTTGATGTTTTCGAAACTTTGCGT
AGTGTAATCTTCCTTGTATTGTAGCGAAGAAAAAAGGATGCGTTGGGAACAGATATAGAA
GACGTAAAACAACCTGAAGAAGGTAACAGGTGGAGTAGCA
Chr coordinates Chr XVI from 366927-368018
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