Yeastract
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YEASTRACT+ INESC-ID IST IBB
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Locus Information

Standard Name ATG5
Systematic Name YPL149W
Alias APG5
Strain S288c
Description Conserved protein involved in autophagy and the Cvt pathway; undergoes conjugation with Atg12p to form a complex involved in Atg8p lipidation; Atg5p-Atg12p conjugate enhances E2 activity of Atg3 by rearranging its catalytic site, also forms a complex with Atg16p; the Atg5-Atg12/Atg16 complex binds to membranes and is essential for autophagosome formation; also involved in methionine restriction extension of chronological lifespan in an autophagy-dependent manner
External sources Open in SGD external link
Open in KEGG external link
Gene Sequence
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Promoter Sequence
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>ATG5 YPL149W
CAAGAACAGATTCCTTTTACGATATCACTACAGCTACACCAGTTGTGACCACTGATAATA
GGCGCAATAAAAACAATAATCTGAAAGAGTCTGTTTTGCCCAGATTTGGGACTCAAAGGC
CATGGACTGGCAAAAGGACGTATACCACGTCCCGCCATGGCAAGAATGCTAGGCGTTCGT
CTAAAAGAGGTCTGTTCAAAATAACTTCTTCAAATACAGACTCTATTATTCAAGAAGTAA
GCTCATCAGAAGAAGAAGATCATAATGTTATCTATAGCAAGGGAAAGGGTCTTCCAACAC
CAGTTTTGCAAACTAAAGGATTAATAGAAAATGGGTTGAACGAACGCGATGAAGAAGGAG
ATGACGAGTATGCAATTCACACTGACGGAGAATTTTCTATCAAACCGCAGTTTTCCGATG
ACGTTATCGACAAACAGAATCATTTGCCCAGCGTGAAGGCTGTGGCAACTAAACGTTCGT
TGAGCGAAGGAAGTAATTGGTCTAGTAGCTATTTGGATTCGGACAATAATCGGCGAAGGG
TATCTTCATTGCTAGTAGAGGATGGGGGGAATCCTACAGCGTAGGTACCGGATAACAGAG
TAACTGGTAAAAACGGCAAAAAATACTGTAAGGAAGTTGTCTATATATGTACATATGGAT
ATTGCGGTATAATAAAAAAGCTTTAAAATTATAAAGAAACCCGACTTTTATCACATATAA
TTATATTATAAAAAAATAATGGCATCTGTATGAACTCGCGATTAAGCTCACTTTTTTCTA
ATGATCGAAGTTTTGTCCGGTTATCCAACTGTGGCAAGAACATCGCGAGGCGGAGCTAAA
CACAGAATTTTTGTAGCGCGATGAGAAACATAACGCCTCTTTAGATAAATTATCATCACC
TTTTTTACACTAAATAATGAAGTAGCATGCTCAGAAGTGCGAATGAATTTTTGTTCTTTT
GGTTCTAGAAGAACGGAGATAGGAAACCTATGATGTAAGT
Chr coordinates Chr XVI from 271310-272194
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