Yeastract
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YEASTRACT+ INESC-ID IST IBB
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Locus Information

Standard Name IPL1
Systematic Name YPL209C
Alias PAC15
Strain S288c
Description Aurora kinase of chromosomal passenger complex; mediates release of mono-oriented kinetochores from microtubules in meiosis I, and kinetochore release from SPB clusters at meiotic exit; helps maintain condensed chromosomes during anaphase; required for SPB cohesion and prevention of multipolar spindle formation; promotes telomerase release at G2/M; Iocalizes to nuclear foci that diffuse upon DNA replication stress; required for inhibition of karyopherin Pse1p upon SAC arrest
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Gene Sequence
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Promoter Sequence
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>IPL1 YPL209C
TCAGGATACCATTTGACTTTGGAACGGTAGTCATGATTTAGAAGATCGACGATGGGAAGC
AGTACAATAGAGTTGTCAGGACAGTTTCTGTTTAGCACATATTCAGGGAATGCTCTTGAA
ATGAATATAAGGTGCGACCATAAAAATGCAGGAAAAGAATACCAGATAGTTGGTCTTTGA
AGTTCTGTTATCTTCAAAATCTTCTCATACAAAGCCTCATATGTCAACTCATCGAGATTA
TGGAAGGTCTGCACATCATCTGCCACTCTTTCCAAGTCAAACATATCTGAAGAACTGACC
AGTTCAAACCACTCTTTAAATATACCTTCGAACTTTTCATGAATCGAATTCCCTATGTTT
GTAGATGATAAACGCTTCAACTCGCTTGGGTTCCAGACCAAGGGCGAATTTAGGCGGGAA
GGCAATGCATCCAAGTAAGGTTTAAATTTATCATTCACACGAACATTGTCCACGATAGTA
TCATTATCCCTATCAAATTTTATTTTTGCGAAGAACAACTTCAGCCATCCGTTGATATTC
TTAGTGGATTCACTTAGCCCAAAAAACTTCATGGGCAGATTCCTTGAAATGACAATCTCG
GGAGGAATCTTGATGCTGGGATTGTCTATATCTTTTTCACATACGCAAATAATGCCCTTA
AGATCGGTATATAAAAACTTGAGTTCCTCTGGCACTATTACACCAAATGACGCACCCCAC
TGAAGTAGTGCTTTTAACGCATCTGATGACATGATAGTCTTCTCTTGTATCTATAACCTT
TGTGCTCCATTTTCCGATACAGCATTGCTTATTGAACAGTAAGTTTAACTTCACGCGTTT
TTCCTGTAAAGCGCTTAATTTGTTTACCATTCTATAAAAACCTTGAGCTAAGGCCAACTG
ATGCAATTGCTCAAGTGAATGCATAAACAAAGCAAGATCATTCTTAGCGCAAAAAAAACT
GGGATTTTGAAATACAACAAAAGAAAGAAGTAAAAAGGGA
Chr coordinates Chr XVI from 157593-156490
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