Locus Information
Locus Info
Protein Info
GO Info
Orthologs
Standard Name
IPL1
Systematic Name
YPL209C
Alias
PAC15
Strain
S288c
Description
Aurora kinase of chromosomal passenger complex; mediates release of mono-oriented kinetochores from microtubules in meiosis I, and kinetochore release from SPB clusters at meiotic exit; helps maintain condensed chromosomes during anaphase; required for SPB cohesion and prevention of multipolar spindle formation; promotes telomerase release at G2/M; Iocalizes to nuclear foci that diffuse upon DNA replication stress; required for inhibition of karyopherin Pse1p upon SAC arrest
External sources
Open in SGD
Open in KEGG
Gene Sequence
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>IPL1 YPL209C
ATGCAACGCAATAGTTTAGTAAATATCAAACTAAACGCTAATTCGCCATCGAAAAAGACC
ACAACAAGACCAAATACGTCCAGGATCAATAAACCATGGAGAATATCCCATTCGCCGCAG
CAAAGAAACCCGAATTCAAAAATACCTTCACCTGTAAGAGAAAAATTGAACAGATTACCT
GTAAACAATAAGAAGTTTTTGGATATGGAAAGCTCCAAAATTCCATCACCTATAAGGAAA
GCGACTTCTTCCAAAATGATACACGAAAATAAGAAGCTACCTAAATTTAAATCCCTATCA
CTCGATGACTTTGAACTGGGGAAGAAATTAGGAAAGGGTAAATTCGGTAAAGTTTATTGC
GTTCGGCACAGGAGTACAGGATATATTTGCGCACTGAAAGTAATGGAGAAGGAAGAAATA
ATAAAGTATAATTTACAGAAACAATTCAGAAGGGAGGTAGAAATACAAACATCGCTAAAT
CATCCGAATCTAACTAAATCATACGGCTATTTTCATGATGAAAAAAGAGTGTACCTGCTA
ATGGAATACTTAGTCAATGGGGAAATGTATAAACTATTGAGGTTACACGGACCCTTCAAC
GATATTTTAGCATCAGATTATATTTATCAAATTGCCAATGCCCTAGATTATATGCATAAA
AAGAATATTATTCATAGAGATATTAAACCTGAAAATATACTAATAGGGTTCAATAATGTC
ATTAAGTTAACGGACTTCGGATGGAGTATAATAAATCCGCCAGAAAATAGAAGGAAAACT
GTCTGTGGGACAATTGACTACCTTTCTCCAGAAATGGTGGAGTCAAGGGAATATGATCAC
ACTATAGATGCATGGGCTCTTGGCGTCCTGGCGTTTGAACTACTGACCGGTGCCCCTCCG
TTCGAAGAAGAAATGAAAGATACTACATATAAAAGGATAGCAGCACTGGATATCAAAATG
CCCAGTAACATTTCTCAGGATGCGCAAGATTTAATACTTAAACTACTAAAATACGACCCC
AAAGATAGAATGCGCCTTGGAGACGTAAAAATGCATCCTTGGATACTAAGAAACAAGCCC
TTTTGGGAAAATAAGCGGTTATAG
Promoter Sequence
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>IPL1 YPL209C
TCAGGATACCATTTGACTTTGGAACGGTAGTCATGATTTAGAAGATCGACGATGGGAAGC
AGTACAATAGAGTTGTCAGGACAGTTTCTGTTTAGCACATATTCAGGGAATGCTCTTGAA
ATGAATATAAGGTGCGACCATAAAAATGCAGGAAAAGAATACCAGATAGTTGGTCTTTGA
AGTTCTGTTATCTTCAAAATCTTCTCATACAAAGCCTCATATGTCAACTCATCGAGATTA
TGGAAGGTCTGCACATCATCTGCCACTCTTTCCAAGTCAAACATATCTGAAGAACTGACC
AGTTCAAACCACTCTTTAAATATACCTTCGAACTTTTCATGAATCGAATTCCCTATGTTT
GTAGATGATAAACGCTTCAACTCGCTTGGGTTCCAGACCAAGGGCGAATTTAGGCGGGAA
GGCAATGCATCCAAGTAAGGTTTAAATTTATCATTCACACGAACATTGTCCACGATAGTA
TCATTATCCCTATCAAATTTTATTTTTGCGAAGAACAACTTCAGCCATCCGTTGATATTC
TTAGTGGATTCACTTAGCCCAAAAAACTTCATGGGCAGATTCCTTGAAATGACAATCTCG
GGAGGAATCTTGATGCTGGGATTGTCTATATCTTTTTCACATACGCAAATAATGCCCTTA
AGATCGGTATATAAAAACTTGAGTTCCTCTGGCACTATTACACCAAATGACGCACCCCAC
TGAAGTAGTGCTTTTAACGCATCTGATGACATGATAGTCTTCTCTTGTATCTATAACCTT
TGTGCTCCATTTTCCGATACAGCATTGCTTATTGAACAGTAAGTTTAACTTCACGCGTTT
TTCCTGTAAAGCGCTTAATTTGTTTACCATTCTATAAAAACCTTGAGCTAAGGCCAACTG
ATGCAATTGCTCAAGTGAATGCATAAACAAAGCAAGATCATTCTTAGCGCAAAAAAAACT
GGGATTTTGAAATACAACAAAAGAAAGAAGTAAAAAGGGA
Chr coordinates
Chr XVI from 157593-156490