Yeastract
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YEASTRACT+ INESC-ID IST IBB
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Locus Information

Standard Name PIN3
Systematic Name YPR154W
Alias LSB2
Strain S288c
Description Negative regulator of actin nucleation-promoting factor activity; interacts with Las17p, a homolog of human Wiskott-Aldrich Syndrome protein (WASP), via an N-terminal SH3 domain, and along with LSB1 cooperatively inhibits the nucleation of actin filaments; short-lived protein whose levels increase in response to thermal stress; induces the formation of the [PIN+] and [RNQ+] prions when overproduced; PIN3 has a paralog, LSB1, that arose from the whole genome duplication
External sources Open in SGD external link
Open in KEGG external link
Gene Sequence
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Promoter Sequence
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>PIN3 YPR154W
CGAAGAAAAAAAGAAACATACTGAAAGTTGATAAATATGCAATAATAAAACCTTTTCCTA
CTCTTGACGCTTCTGTATAAGATAAAAACTGCCAACAAGATCAGTTCCAACTTCCTGCCG
TATTATGAGGTATGTTATTCATTACCAAGACTATATCCGCCACGGCTGGATGCAGGCATC
GCTCCCTGTGGCTTAAGAAAATAATAGGCACAAAACTAACAATAAAAACATCCACTACTC
TGTCGCATGTTCCCTGTGCTCAGATCATTCGTAACAAATAACGATATACCTGTTGGATAT
GTAACGCCAAAATTCCCCTCATTATACTGGCCCATCAACAACTCGAAGTATAATACTGCA
TTCTTATACTATATATCTGACATTTGGAAATTTTCGCTGTACTGGACTTTGATCTTTAAT
GGTGCATTTTACGTTACTGCTGGTGTGTATGCTAGCTTGACCCATAGAAAGAAGGCTGGA
AGTGTATGGATATTCGTCATGTACGTCTTATACGGAGGCGTTCAAGGCTTGACGACTGGT
ACAGTTATGGGGTTTTTAATAGGTGCGATCTATAGATCTGGTTTATTTTCTATGTCTACA
TGGGTCCCACTTTGTTGCGCAGTAGTCCAAATCCTTTTCGATGTGGTGCTAAGTTATTCC
ATGGTTGGTTCCGTTATGTGAAAGCTTCTGTCAAGAAAAAACAAGAAGGGGTTTACTGAT
TTGATGATAAAAGTTAGCAGCAACTTTTGAATGAGAATGTGCCATCCTTCACGTAAAGAG
CCTAATACTCTTTCTTCAAAGCGCTAGATTGTTCTAAACGTTTCTTTAACTATTGTTTTC
GTTCGTGCAGCGTGATTAACCGAGCCTCCTTCGAGGCGGGGATGGATATTGTAAGCTGCA
TATATAGTCGAACCTCAAATCGGTTGAGACAATAGGCAAAGTGCCCACATTGGCGCAAAC
ACAAGAACATTAGGAAAGAAGGCAATCTGATATTTCAAAA
Chr coordinates Chr XVI from 834565-835212
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