Protein Information
Locus Info
Protein Info
GO Info
Orthologs
Protein Name
Aft2p
Description
Iron-regulated transcriptional activator; activates genes involved in intracellular iron use and required for iron homeostasis and resistance to oxidative stress; AFT2 has a paralog, AFT1, that arose from the whole genome duplication
Aminoacid Sequence
Download FASTA
>AFT2 YPL202C
MKAKSMKSIISVPISVSKTGKMKLTASPDNLASMMSKDQNKLIHLDPVPSFEDRHEIKPW
LQKIFYPQGIDIVIERSDSSKVTFKCRSVRSKVGLNPKSKGSSSRSHACPFRIRAAYSVR
LQKWNVVVMNNIHSHELRFDLITKTDDYKKFKENLRQKNDEKAIKTFDELEYKASLNLPL
VTPIISCDCGLTKEIEAFNNIFLPLSNPPLTSKKNLLKTNKNSVSKIKSRQMDNSKPRPR
LKTKLDADLHDTGFLDNFKTRNSCVKIEKEDSLTNLNEIDFTNMFCNDNFIQNYNQGLME
LLTEPTPGPSSSSCILPSTPTRPLSQSKMDIALSESTTSSPNFMETDAPYGDEIIKVSKD
TKSNAPTADTDIATNLGKERNENFGMLNYNYEALLHFNDEHFNELNSIDPALISKY*
Transcription Factor Binding site(s)
YRCACCCR
TGCACCC
GGCACCC
CGCACCC
gGGGTGYg
gGGTGYg
gGGTGY
Regulon
See Venn diagram regulon
Documented targets
See documented regulated genes
Potential targets
See potential regulated genes
(Attention! Can return hundreds of genes)
External source
Open in SGD