S.cerevisiae - Yeastract

Protein Information

Protein Name	Cbf1p
Description	Basic helix-loop-helix (bHLH) protein; forms homodimer to bind E-box consensus sequence CACGTG present at MET gene promoters and centromere DNA element I (CDEI); affects nucleosome positioning at this motif; associates with other transcription factors such as Met4p and Isw1p to mediate transcriptional activation or repression; associates with kinetochore proteins, required for chromosome segregation; protein abundance increases in response to DNA replication stress
Aminoacid Sequence Download FASTA	>CBF1 YJR060W MNSLANNNKLSTEDEEIHSARKRGYNEEQNYSEARKKQRDQGLLSQESNDGNIDSALLSE GATLKGTQSQYESGLTSNKDEKGSDDEDASVAEAAVAATVNYTDLIQGQEDSSDAHTSNQ TNANGEHKDSLNGERAITPSNEGVKPNTSLEGMTSSPMESTQQSKNDMLIPLAEHDRGPE HQQDDEDNDDADIDLKKDISMQPGRRGRKPTTLATTDEWKKQRKDSHKEVERRRRENINT AINVLSDLLPVRESSKAAILACAAEYIQKLKETDEANIEKWTLQKLLSEQNASQLASANE KLQEELGNAYKEIEYMKRVLRKEGIEYEDMHTHKKQENERKSTRSDNPHEA*
Transcription Factor Binding site(s)	CACGTG RTCACGTG RTCACRTG TCACGTT VCACGtg gaxcxgtCACGTGactxxtcg DxcxgatCACGTGaYxDgxxxa CACGTGAYc gCACGTGa CACGTGAcc axCAcgtg CAcgtga AAAGCACGTG AAAGCACGTGAACA AAAGCACGTGAG AAAGCACGTGCNCA AAAGCACGTGGNC AAANCACGTG AAATCACGT AAATCACGTGACA AAATCACGTGCGA AAATCACGTGGT AAATCACGTGT AAATCACGTTT AACCACGTG AACCACGTGTAT AAGCACGT AAGTCACGTGAAA AAGTCACGTGCAA AAGTCACGTGCAC AAGTCACGTGG AAGTCACGTGTT AANCACGTG AATCACGTGGGA AATCACGTGTG ACATCACGTGAAA ACATCACGTGAAT ACATCACGTGATA ACATCACGTGCACA AGAGCACGTGCGA AGATCACG AGATCACGTGAAT AGATCACGTGCAA AGATCACGTGCACA AGATCACGTGGAG AGCACNTGC AGGCACGTGAT AGGCACGTGCTA AGGTCACGTGAAG AGGTCACGTGANC AGGTCACGTGC AGGTCACGTGTTT AGGTCACGTT AGTCACGTGANA AGTCANGTGA AGTCANGTGAT ANGCACGTG ANGCACGTGC ANTCACGTGATC ATATCACGTGAAT ATATCACGTGATT ATATCACGTGCTT ATATCACGTGGA ATCACATGAC ATCACATGATA ATGGCACGTGTAT ATGTCACGTGCAC ATGTCACGTGCACA ATGTCACGTGCTT ATGTCACGTTTT ATNTCACGTGG CACGTGAAA CACGTGAAT CACGTGAG CACGTGGAA CAGCACGTG CAGCACGTGGG CAGTCACGTGANA CAGTCACGTGTAT CANCACGTG CANCACGTGAG CANTCACGTGATC CCATCACGTGATA CCATCACGTGTA CCGTCACGTGGAA CGATCACGTGAAT CGATCACGTGGAA CGATCACGTGGTC CGGCACGTGAT CGTCACGTGCAC CGTCACGTGGGA CGTCACGTGTAA CNTCACGTGCNA CTATCACGTGATA CTATCACGTGCCA CTATCACGTGT CTATCACGTGTG CTATCACGTGTTT GAAGCACGTG GAGCACGTGA GANCACGTGA GATCACATG GATCACGTGATC GATCACGTGCTA GATCACGTGGG GATCANGTGA GATCANGTGAT GCACGTGAAC GCACGTGCNC GCAGCACGTG GCATCACGTGAAA GCATCACGTGACT GGCACGTGAT GGCCACGTGA GGGTCACGTGAT GGGTCACGTGCAT GGGTCACGTGCGG GGGTCACGTGGGA GGGTCACGTGTAT GGGTCACGTGTGT GGTCACATGGT GGTCACGTGANT GGTCACGTGCGG GGTCACGTGCTCA GGTCACGTGTAA GGTCANGTGA GGTCANGTGAT GNTCACGTGCTC GTCANGTGA GTCANGTGAT GTGTCACGTGAG GTGTCACGTGANA GTGTCACGTGATA GTGTCACGTGATC TAAGCACGTGCNCA TAAGCACGTGCNG TAATCACGTGACT TAATCACGTGATC TAATCACGTGCG TAGCACGTG TAGTCACGTGANA TAGTCACGTGCG TAGTCACGTGCTC TAGTCACGTGGG TAGTCACGTGGT TAGTCACGTGGTC TATATCACGTGATC TATATCACGTGCTCA TATCACGTGCAA TATCACGTTTT TATCANGTG TCACGTGANC TCACGTGATA TCACGTGATC TCACGTGATT TCACGTGCTCA TCATCACGTGGA TGATCACGTGAAA TGATCACGTGATA TGATCACGTGATT TGATCACGTGCGA TGATCACGTT TGCCACGTGA TGGCACGTGA TGGCACGTGCNA TGGTCACGTGAAT TGGTCACGTGCAA TGGTCACGTGCAT TGGTCACGTGCG TGGTCACGTGCGG TGGTCACGTGG TGGTCACGTGGA TGGTCACGTGGTC TGGTCACGTGGTT TGGTCACGTGTG TGNTCACGTGA TGTCACATGAC TGTCACGTGCAA TTATCACGTGACT TTATCACGTGAT TTATCACGTGATC TTATCACGTGTG TTCATCACGTGCG TTCATCACGTGTGT TTGATCACGTGAAA TTGATCACGTGACA TTGATCACGTGATT TTNTCACGTGAT AAACCACGTGAAAA AAACCACGTGAG AAAGCACGTGTG AAANCACGTGTA AAGTCACGTT AAGTCACGTTT AATCACGTTTT ACATCACGTGTG ACATCACGTGTGT ACATCACGTT ACATCACGTTT AGATCACGTTT AGCCACGTGTA AGGCACGTGCTGC AGGCACGTGGA AGGCACGTGGT AGGCACGTGTAT AGGCACGTGTG AGTCACGTTT AGTCANGTG ANCACGTGC ANCACGTGCNC ANGCACGTGAACA ANGCACGTGGT ANTCACGTGCAA ANTCACGTGCTC ATCACATG ATCACATGA ATCACATGGT ATGGCACGTGAG ATGGCACGTGCGA ATGGCACGTGTG ATNTCACGTGAAT ATNTCACGTGAT CACATGAC CACATGAT CACGTGAACA CACGTGAAG CACGTGCAA CACGTGCGA CACGTGCGG CACGTGCTGC CACGTGGAG CACGTGGGA CACGTGGNC CACGTGGT CACGTGTT CACGTGTTT CAGCACGTGC CAGCACGTGTTT CAGTCACGTT CANTCACGTGTAA CCATCACGTGGA CCATCACGTGTT CCGTCACGTGAAG CCGTCACGTGG CGATCACGTGTG CGGCACGTGAG CGTCACGTTTT CNTCACGTGCTG GAGCACGTGGT GANCACGTGGTC GATCACATGA GATCACGTTTT GCACGTGCAC GCACGTGCG GCACGTGGAA GCAGCACGTGGG GCCACGTGTTT GGCACGTGAAT GGCCACGTGCAG GGGTCACGTTT GGTCACATG GGTCACATGATA GGTCANGTG GNTCACGTGGTT GTCACATG GTCACATGATA TAGTCACGTTT TAGTCACGTTTT TATATCACGTT TATCACATG TATCACGTGGAA TATCACGTT TATCANGTGNT TCACATGA TCACATGAC TCACGTGC TCACGTGCTA TCACGTGGAG TCATCACGTGT TGAGCACGT TGATCACG TGATCACGTTT TGCCACGTGAAA TGCCACGTGC TGCCACGTGCGA TGGCACGTGGG TGNGCACGTGGT TGTCACATG TGTCACATGAT TGTCACGTTT TNTCACGTGAG TTATCACGT TTCATCACGTGTAA TTGATCACGTGGG TTGATCACGTT TTGATCACGTTT TTNTCACGTGATA TTNTCACGTGCTA AAAGCACGT AAANCACGTGCAG AACCACGTGTT AAGCACGTGTA AATCACGT ACATCACGTGGAA AGGCACGTGTTT AGGTCACGTTTT AGTCACGT AGTCACGTTTT ATGTCACGT ATNTCACGTGTA CACGTGCAG CACGTGTAT CANCACGTGCAT CANCACGTGCNA CANTCACGTGCTTA CTATCACGTT GANCACGTGAACA GANCACGTGAAT GATCACATGGT GATCACGTT GCACGTGAAAA GCACGTGTTTC GCAGCACGT GCATCACGTT GGCACGTGG TAGCACGTGC TATCACATGAT TCATCACGTGTA TGCCACGTGGG TTATCACG TTATCACGTTT TTNTCACGTGC
Regulon	See Venn diagram regulon
Documented targets	See documented regulated genes
Potential targets	See potential regulated genes (Attention! Can return hundreds of genes)
External source	Open in SGD